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Breed profile · FDA CVM July 2026 extract

Samoyed adverse-event record

Adverse-event filings for Samoyed (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#136 of 510
by report volume (all breeds)
558
FDA CVM reports on file
5.7%
death-coded share of reports
#106 of 275
by death-coded share (≥50 reports)

How the 558 reports break down

By recorded gender -- every report on file for Samoyed, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 45 33.75 22.5 11.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Samoyed drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Samoyed ranks #136 of 510 by total reports (558) and #106 of 275 by death-coded share (5.7%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#136
This breed, reports of 510
#106
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Samoyed has 558 reports now versus 548 in that prior snapshot: 10 more (1.8%).

Report change
+10
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Samoyed changes

Total Reports

558

Above-median volume

Deaths Reported

32

of 558 reports

Death-coded share of reports

5.7%

Above-median death-coded share

Avg Age at Report

6.2 yr

25.9 kg avg weight

Breed Safety Scorecard

D (44/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
5.7%

Share of reports coded as a fatality

Euthanasia rate F
3.2%

Share of reports resulting in euthanasia

Full recovery rate C-
29.2%

Share of reports coded "Recovered/Normal"

5-year trend B-
-8%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Samoyed death-coded reports 5.7%
Cross-breed median

5.7% of 558 samoyed reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Samoyed's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

6% 61st percentile Higher share than 61% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Samoyed 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 25.9 kg (57.1 lbs)

Top Reported Reactions

Vomiting 91
Diarrhoea 59
Lethargy (see also Central nervous system depression in 'Neurological') 40
Emesis 35
Lack of efficacy - NOS 30
Anorexia 29
Lack of efficacy (endoparasite) - hookworm 25
Lack of efficacy (ectoparasite) - flea 23

Most Referenced Drugs

Milbemycin Oxime + Spinosad 65
Afoxolaner 46
Ivermectin + Pyrantel As Pamoate Salt 45
Pyrantel Pamoate;Sarolaner 43
Bedinvetmab 31
Fluralaner 13.64% 12-Week Chew 28
Fluralaner Chew Tablets 25
Carprofen 24

Outcome Breakdown

Recovered/Normal
163 (31.3%)
Ongoing
156 (29.9%)
Outcome Unknown
152 (29.2%)
Euthanized
18 (3.5%)
Recovered with Sequela
18 (3.5%)
Died
14 (2.7%)

Gender Distribution

Male 277 (49.6%)
Female 272 (48.7%)
Unknown 8 (1.4%)
Mixed 1 (0.2%)

Reports by Year

Year Reports Trend
2010 19
2011 35
2012 27
2013 32
2014 28
2015 35
2016 30
2017 40
2018 42
2019 39
2020 36
2021 40
2022 23
2023 41
2024 45
2025 37
2026 9

Samoyed: high-volume FDA adverse-event cohort

Signature read: 558 reports place Samoyed in the upper third of breed filing volume (#136 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Samoyed sits at #136 of 510 by report volume among all breeds and #113 of 298 among dog breeds, with 558 reports and 32 (5.7%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #106 of 275. Mean age at report: 6.2 years, average weight 25.9 kg (57.1 lbs).

Top reported signs: Vomiting (91), Diarrhoea (59), Lethargy (see also Central nervous system depression in 'Neurological') (40). Most-referenced drug: Milbemycin Oxime + Spinosad (65 reports), followed by Afoxolaner (46) and Ivermectin + Pyrantel As Pamoate Salt (45).

Outcome coding on 521 status-recorded reports is dominated by Recovered/Normal (31.3%). Annual submissions ranged 9-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Bullmastiff
548 reports · 6.4% death-coded
Sheepdog - Old English
568 reports · 4.0% death-coded
Mastiff (unspecified)
569 reports · 9.8% death-coded
Cattle Dog (unspecified)
588 reports · 5.1% death-coded
Spaniel - King Charles
525 reports · 3.0% death-coded
Black Mouth Cur
592 reports · 2.0% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Samoyed drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (5.7% death-coded here).

Norwegian Forest 5.7% · Cat Egyptian Mau 5.3% · Cat Crossbred Feline/cat 6.3% · Cat Scottish Fold Longhair 4.8% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (25.9 kg here).

Mixed (Sheep) 24.9 kg · Sheep Crossbred Caprine/goat 21.7 kg · Goat Pygmy 20.3 kg · Goat Fish (other) 32.4 kg · Fish

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Samoyed? ▼
There are 558 adverse event reports involving Samoyed in the FDA database, of which 32 were death-coded (5.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Samoyed ranks #136 of 510 by report volume among all breeds PlainBreed indexes (#113 of 298 among dog breeds).
Where does Samoyed sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Samoyed is #136 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #113 of 298. Among breeds with at least 50 reports, its death-coded share ranks #106 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Samoyed? ▼
The most commonly reported adverse reactions for Samoyed are Vomiting (91 reports), Diarrhoea (59 reports), Lethargy (see also Central nervous system depression in 'Neurological') (40 reports), Emesis (35 reports), Lack of efficacy - NOS (30 reports).
What drugs are most frequently associated with Samoyed adverse events? ▼
The drugs most frequently referenced in Samoyed adverse event reports are Milbemycin Oxime + Spinosad (65 reports), Afoxolaner (46 reports), Ivermectin + Pyrantel As Pamoate Salt (45 reports), Pyrantel Pamoate;Sarolaner (43 reports), Bedinvetmab (31 reports).
What is the average age of Samoyed in adverse event reports? ▼
The average age of Samoyed at the time of adverse event reports is 6.2 years, with an average weight of 25.9 kg (57.1 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Samoyed (Dog), extract as of July 2026 extract. 558 reports · 32 death-coded (5.7% of reports, not a mortality rate) · #136 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →