Total Reports
535
FDA CVM filings
Dog /
FDA CVM · 2025 release 535 reports on file
Samoyed - FDA Adverse Event Profile
Adverse-event records for Samoyed (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 535 reports on file, Samoyed sits at #135 among dog breeds by volume; death-coded share is 5.8% (31 reports).
- #135
- most-reported dog breed
- 5.8%
- death-coded report share
- 90
- Vomiting - top reaction
- 6.1 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
31
of 535 reports
Death Rate
5.8%
death-coded share
Avg Age at Report
6.1 yr
25.8 kg avg weight
Death-Coded Outcome Share
Samoyed death-coded reports 5.8%
Cross-breed median
5.8% of 535 samoyed reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 25.8 kg (56.9 lbs)
Top Reported Reactions
Vomiting 90
Diarrhoea 59
Lethargy (see also Central nervous system depression in 'Neurological') 40
Emesis 35
Anorexia 28
Lack of efficacy - NOS 28
Lack of efficacy (endoparasite) - hookworm 24
Other abnormal test result NOS 22
Most Referenced Drugs
Milbemycin Oxime + Spinosad 65
Afoxolaner 45
Ivermectin + Pyrantel As Pamoate Salt 45
Pyrantel Pamoate;Sarolaner 41
Bedinvetmab 26
Fluralaner Chew Tablets 25
Fluralaner 13.64% 12-Week Chew 24
Carprofen 22
Outcome Breakdown
Recovered/Normal
162 (32.5%)
Outcome Unknown
145 (29.1%)
Ongoing
142 (28.5%)
Euthanized
18 (3.6%)
Recovered with Sequela
18 (3.6%)
Died
13 (2.6%)
Gender Distribution
Male 264 (49.3%)
Female 262 (49.0%)
Unknown 8 (1.5%)
Mixed 1 (0.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 19 | |
| 2011 | 35 | |
| 2012 | 27 | |
| 2013 | 32 | |
| 2014 | 28 | |
| 2015 | 35 | |
| 2016 | 30 | |
| 2017 | 40 | |
| 2018 | 42 | |
| 2019 | 39 | |
| 2020 | 36 | |
| 2021 | 40 | |
| 2022 | 23 | |
| 2023 | 39 | |
| 2024 | 45 | |
| 2025 | 25 | |
Samoyed Pet Health Insights
Samoyed accounts for 535 FDA adverse event reports, ranking #135 by volume among dog breeds, with 31 reports (5.8%) coded as a death outcome. Mean age at report: 6.1 years, average weight 25.8 kg (56.9 lbs).
Top reported signs: Vomiting (90), Diarrhoea (59), Lethargy (see also Central nervous system depression in 'Neurological') (40). Most-referenced drug: Milbemycin Oxime + Spinosad (65 reports), followed by Afoxolaner (45) and Ivermectin + Pyrantel As Pamoate Salt (45).
Outcome coding on 498 status-recorded reports is dominated by Recovered/Normal (32.5%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Samoyed? ▼
There are 535 adverse event reports involving Samoyed in the FDA database, with 31 reports involving death (5.8% death rate). Samoyed ranks #135 by report volume.
What are the most common adverse reactions reported for Samoyed? ▼
The most commonly reported adverse reactions for Samoyed are Vomiting (90 reports), Diarrhoea (59 reports), Lethargy (see also Central nervous system depression in 'Neurological') (40 reports), Emesis (35 reports), Anorexia (28 reports).
What drugs are most frequently associated with Samoyed adverse events? ▼
The drugs most frequently referenced in Samoyed adverse event reports are Milbemycin Oxime + Spinosad (65 reports), Afoxolaner (45 reports), Ivermectin + Pyrantel As Pamoate Salt (45 reports), Pyrantel Pamoate;Sarolaner (41 reports), Bedinvetmab (26 reports).
What is the average age of Samoyed in adverse event reports? ▼
The average age of Samoyed at the time of adverse event reports is 6.1 years, with an average weight of 25.8 kg (56.9 lbs).
Does a high number of adverse event reports mean Samoyed is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Samoyed safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.