Total Reports
389
FDA CVM filings
Dog /
FDA CVM · 2025 release 389 reports on file
Retriever - Flat-coated - FDA Adverse Event Profile
Adverse-event records for Retriever - Flat-coated (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Retriever - Flat-coated ranks #152 by report volume among dog breeds - 14 of 389 reports (3.6%) recorded a death outcome.
- #152
- most-reported dog breed
- 3.6%
- death-coded report share
- 57
- Vomiting - top reaction
- 5.3 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
14
of 389 reports
Death Rate
3.6%
death-coded share
Avg Age at Report
5.3 yr
29.7 kg avg weight
Death-Coded Outcome Share
Retriever - Flat-coated death-coded reports 3.6%
Cross-breed median
3.6% of 389 retriever - flat-coated reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 29.7 kg (65.5 lbs)
Top Reported Reactions
Vomiting 57
Lethargy (see also Central nervous system depression in 'Neurological') 37
Diarrhoea 34
Lack of efficacy (endoparasite) - hookworm 29
Emesis 28
Digestive tract disorder NOS 24
Lack of efficacy - NOS 23
Lack of efficacy (endoparasite) - heartworm 23
Most Referenced Drugs
Milbemycin Oxime + Spinosad 55
Ivermectin + Pyrantel As Pamoate Salt 55
Afoxolaner 26
Pyrantel Pamoate;Sarolaner 24
Spinosad 20
Carprofen 20
Milbemycin Oxime + Praziquantel 20
Oclacitinib Maleate 15
Outcome Breakdown
Outcome Unknown
127 (35.2%)
Recovered/Normal
112 (31.0%)
Ongoing
95 (26.3%)
Recovered with Sequela
13 (3.6%)
Euthanized
8 (2.2%)
Died
6 (1.7%)
Gender Distribution
Male 229 (58.9%)
Female 154 (39.6%)
Unknown 4 (1.0%)
Mixed 2 (0.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 8 | |
| 2011 | 23 | |
| 2012 | 22 | |
| 2013 | 32 | |
| 2014 | 34 | |
| 2015 | 28 | |
| 2016 | 32 | |
| 2017 | 35 | |
| 2018 | 32 | |
| 2019 | 25 | |
| 2020 | 26 | |
| 2021 | 12 | |
| 2022 | 16 | |
| 2023 | 17 | |
| 2024 | 34 | |
| 2025 | 13 | |
Retriever - Flat-coated Pet Health Insights
Retriever - Flat-coated accounts for 389 FDA adverse event reports, ranking #152 by volume among dog breeds, with 14 reports (3.6%) coded as a death outcome. Mean age at report: 5.3 years, average weight 29.7 kg (65.5 lbs).
Top reported signs: Vomiting (57), Lethargy (see also Central nervous system depression in 'Neurological') (37), Diarrhoea (34). Most-referenced drug: Milbemycin Oxime + Spinosad (55 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (55) and Afoxolaner (26).
Outcome coding on 361 status-recorded reports is dominated by Outcome Unknown (35.2%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Collie - Rough-haired
357 reports · 5.0% death rate
Japanese Chin (Spaniel)
357 reports · 3.6% death rate
Terrier - Fox Wire
426 reports · 5.2% death rate
Sheepdog (unspecified)
347 reports · 2.9% death rate
Schnauzer - Giant
346 reports · 5.8% death rate
Terrier - Tibetan
439 reports · 2.7% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Retriever - Flat-coated? ▼
There are 389 adverse event reports involving Retriever - Flat-coated in the FDA database, with 14 reports involving death (3.6% death rate). Retriever - Flat-coated ranks #152 by report volume.
What are the most common adverse reactions reported for Retriever - Flat-coated? ▼
The most commonly reported adverse reactions for Retriever - Flat-coated are Vomiting (57 reports), Lethargy (see also Central nervous system depression in 'Neurological') (37 reports), Diarrhoea (34 reports), Lack of efficacy (endoparasite) - hookworm (29 reports), Emesis (28 reports).
What drugs are most frequently associated with Retriever - Flat-coated adverse events? ▼
The drugs most frequently referenced in Retriever - Flat-coated adverse event reports are Milbemycin Oxime + Spinosad (55 reports), Ivermectin + Pyrantel As Pamoate Salt (55 reports), Afoxolaner (26 reports), Pyrantel Pamoate;Sarolaner (24 reports), Spinosad (20 reports).
What is the average age of Retriever - Flat-coated in adverse event reports? ▼
The average age of Retriever - Flat-coated at the time of adverse event reports is 5.3 years, with an average weight of 29.7 kg (65.5 lbs).
Does a high number of adverse event reports mean Retriever - Flat-coated is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Retriever - Flat-coated safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.