Total Reports
426
FDA CVM filings
Dog /
FDA CVM · 2025 release 426 reports on file
Terrier - Fox Wire - FDA Adverse Event Profile
Adverse-event records for Terrier - Fox Wire (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 426 reports on file, Terrier - Fox Wire sits at #149 among dog breeds by volume; death-coded share is 5.2% (22 reports).
- #149
- most-reported dog breed
- 5.2%
- death-coded report share
- 97
- Vomiting - top reaction
- 6.4 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
22
of 426 reports
Death Rate
5.2%
death-coded share
Avg Age at Report
6.4 yr
9.9 kg avg weight
Death-Coded Outcome Share
Terrier - Fox Wire death-coded reports 5.2%
Cross-breed median
5.2% of 426 terrier - fox wire reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 9.9 kg (21.8 lbs)
Top Reported Reactions
Vomiting 97
Lethargy (see also Central nervous system depression in 'Neurological') 51
Diarrhoea 29
Emesis 27
Lack of efficacy (endoparasite) - heartworm 27
Lack of efficacy (ectoparasite) - flea 22
Lack of efficacy - NOS 20
Other abnormal test result NOS 18
Most Referenced Drugs
Milbemycin Oxime + Spinosad 93
Ivermectin + Pyrantel As Pamoate Salt 36
Afoxolaner 35
Oclacitinib Maleate 31
Milbemycin Oxime + Praziquantel 24
Trilostane 20
Pyrantel Pamoate;Sarolaner 20
Spinosad 16
Outcome Breakdown
Recovered/Normal
149 (35.0%)
Outcome Unknown
138 (32.4%)
Ongoing
106 (24.9%)
Died
12 (2.8%)
Recovered with Sequela
11 (2.6%)
Euthanized
10 (2.3%)
Gender Distribution
Male 212 (49.8%)
Female 207 (48.6%)
Unknown 7 (1.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 8 | |
| 2012 | 35 | |
| 2013 | 29 | |
| 2014 | 29 | |
| 2015 | 25 | |
| 2016 | 45 | |
| 2017 | 35 | |
| 2018 | 35 | |
| 2019 | 23 | |
| 2020 | 31 | |
| 2021 | 38 | |
| 2022 | 20 | |
| 2023 | 35 | |
| 2024 | 23 | |
| 2025 | 15 | |
Terrier - Fox Wire Pet Health Insights
Terrier - Fox Wire accounts for 426 FDA adverse event reports, ranking #149 by volume among dog breeds, with 22 reports (5.2%) coded as a death outcome. Mean age at report: 6.4 years, average weight 9.9 kg (21.8 lbs).
Top reported signs: Vomiting (97), Lethargy (see also Central nervous system depression in 'Neurological') (51), Diarrhoea (29). Most-referenced drug: Milbemycin Oxime + Spinosad (93 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (36) and Afoxolaner (35).
Outcome coding on 426 status-recorded reports is dominated by Recovered/Normal (35.0%). Annual submissions ranged 2,011-2,025 across 15 years on file.
Dog Breeds With a Similar Report Volume
Terrier - Tibetan
439 reports · 2.7% death rate
Mastiff (unspecified)
441 reports · 11.8% death rate
Shepherd Dog - Anatolian
447 reports · 4.7% death rate
Basenji
452 reports · 5.5% death rate
Coonhound - Treeing Walker
455 reports · 2.9% death rate
Retriever - Flat-coated
389 reports · 3.6% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Terrier - Fox Wire? ▼
There are 426 adverse event reports involving Terrier - Fox Wire in the FDA database, with 22 reports involving death (5.2% death rate). Terrier - Fox Wire ranks #149 by report volume.
What are the most common adverse reactions reported for Terrier - Fox Wire? ▼
The most commonly reported adverse reactions for Terrier - Fox Wire are Vomiting (97 reports), Lethargy (see also Central nervous system depression in 'Neurological') (51 reports), Diarrhoea (29 reports), Emesis (27 reports), Lack of efficacy (endoparasite) - heartworm (27 reports).
What drugs are most frequently associated with Terrier - Fox Wire adverse events? ▼
The drugs most frequently referenced in Terrier - Fox Wire adverse event reports are Milbemycin Oxime + Spinosad (93 reports), Ivermectin + Pyrantel As Pamoate Salt (36 reports), Afoxolaner (35 reports), Oclacitinib Maleate (31 reports), Milbemycin Oxime + Praziquantel (24 reports).
What is the average age of Terrier - Fox Wire in adverse event reports? ▼
The average age of Terrier - Fox Wire at the time of adverse event reports is 6.4 years, with an average weight of 9.9 kg (21.8 lbs).
Does a high number of adverse event reports mean Terrier - Fox Wire is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Fox Wire safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.