Total Reports
357
FDA CVM filings
Dog /
FDA CVM · 2025 release 357 reports on file
Japanese Chin (Spaniel) - FDA Adverse Event Profile
Adverse-event records for Japanese Chin (Spaniel) (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Japanese Chin (Spaniel)'s FDA record: #155 most-reported dog breed, 357 total reports, 3.6% death-coded (13 reports).
- #155
- most-reported dog breed
- 3.6%
- death-coded report share
- 69
- Vomiting - top reaction
- 6.1 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
13
of 357 reports
Death Rate
3.6%
death-coded share
Avg Age at Report
6.1 yr
5.3 kg avg weight
Death-Coded Outcome Share
Japanese Chin (Spaniel) death-coded reports 3.6%
Cross-breed median
3.6% of 357 japanese chin (spaniel) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 5.3 kg (11.7 lbs)
Top Reported Reactions
Vomiting 69
Lethargy (see also Central nervous system depression in 'Neurological') 57
Lack of efficacy (ectoparasite) - flea 51
Diarrhoea 36
Seizure NOS 27
Emesis 24
Anorexia 22
Lack of efficacy - NOS 22
Most Referenced Drugs
Milbemycin Oxime + Spinosad 72
Spinosad 50
Afoxolaner 30
Ivermectin + Pyrantel As Pamoate Salt 24
Pimobendan 18
Nitenpyram 12
Pyrantel Pamoate;Sarolaner 12
Bedinvetmab 12
Outcome Breakdown
Recovered/Normal
123 (38.3%)
Outcome Unknown
119 (37.1%)
Ongoing
57 (17.8%)
Died
10 (3.1%)
Recovered with Sequela
9 (2.8%)
Euthanized
3 (0.9%)
Gender Distribution
Female 172 (48.2%)
Male 169 (47.3%)
Unknown 16 (4.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 20 | |
| 2011 | 22 | |
| 2012 | 38 | |
| 2013 | 21 | |
| 2014 | 34 | |
| 2015 | 29 | |
| 2016 | 39 | |
| 2017 | 28 | |
| 2018 | 14 | |
| 2019 | 21 | |
| 2020 | 19 | |
| 2021 | 9 | |
| 2022 | 12 | |
| 2023 | 19 | |
| 2024 | 19 | |
| 2025 | 13 | |
Japanese Chin (Spaniel) Pet Health Insights
Japanese Chin (Spaniel) accounts for 357 FDA adverse event reports, ranking #155 by volume among dog breeds, with 13 reports (3.6%) coded as a death outcome. Mean age at report: 6.1 years, average weight 5.3 kg (11.7 lbs).
Top reported signs: Vomiting (69), Lethargy (see also Central nervous system depression in 'Neurological') (57), Lack of efficacy (ectoparasite) - flea (51). Most-referenced drug: Milbemycin Oxime + Spinosad (72 reports), followed by Spinosad (50) and Afoxolaner (30).
Outcome coding on 321 status-recorded reports is dominated by Recovered/Normal (38.3%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Japanese Chin (Spaniel)? ▼
There are 357 adverse event reports involving Japanese Chin (Spaniel) in the FDA database, with 13 reports involving death (3.6% death rate). Japanese Chin (Spaniel) ranks #155 by report volume.
What are the most common adverse reactions reported for Japanese Chin (Spaniel)? ▼
The most commonly reported adverse reactions for Japanese Chin (Spaniel) are Vomiting (69 reports), Lethargy (see also Central nervous system depression in 'Neurological') (57 reports), Lack of efficacy (ectoparasite) - flea (51 reports), Diarrhoea (36 reports), Seizure NOS (27 reports).
What drugs are most frequently associated with Japanese Chin (Spaniel) adverse events? ▼
The drugs most frequently referenced in Japanese Chin (Spaniel) adverse event reports are Milbemycin Oxime + Spinosad (72 reports), Spinosad (50 reports), Afoxolaner (30 reports), Ivermectin + Pyrantel As Pamoate Salt (24 reports), Pimobendan (18 reports).
What is the average age of Japanese Chin (Spaniel) in adverse event reports? ▼
The average age of Japanese Chin (Spaniel) at the time of adverse event reports is 6.1 years, with an average weight of 5.3 kg (11.7 lbs).
Does a high number of adverse event reports mean Japanese Chin (Spaniel) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Japanese Chin (Spaniel) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.