Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
62
Total Reports
3
Deaths Reported
480.0%
Death Rate
6.5 yr
Avg Age at Report
Average weight at time of report: 31.3 kg (69.0 lbs)
Top Reported Reactions
Vomiting 15
Diarrhoea 7
Ataxia 7
Emesis 6
Behavioural disorder NOS 5
Lack of efficacy (ectoparasite) - flea 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Other abnormal test result NOS 4
Uncoded sign 4
Panting 3
Death 3
Seizure NOS 3
Tremor of limb 3
Lack of efficacy - NOS 3
Stumbling gait 2
Most Referenced Drugs
Spinosad 11
Milbemycin Oxime + Spinosad 10
Afoxolaner 8
Ivermectin + Pyrantel As Pamoate Salt 6
Nitenpyram 5
Carprofen 4
Fluralaner Chew Tablets 4
Sarolaner 3
Imidacloprid, Flumethrin 3
Imidacloprid + Pyriproxyfen 3
Shampoo 3
Firocoxib 2
Milbemycin, Lufenuron 2
Bedinvetmab 2
Cyclosporine 1
Outcome Breakdown
Recovered/Normal
19 (36.5%)
Outcome Unknown
19 (36.5%)
Ongoing
11 (21.2%)
Died
3 (5.8%)
Gender Distribution
Male 32 (51.6%)
Female 29 (46.8%)
Unknown 1 (1.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 8 | |
| 2011 | 2 | |
| 2012 | 8 | |
| 2013 | 4 | |
| 2014 | 3 | |
| 2015 | 4 | |
| 2016 | 4 | |
| 2017 | 5 | |
| 2018 | 6 | |
| 2019 | 3 | |
| 2020 | 3 | |
| 2022 | 7 | |
| 2023 | 1 | |
| 2024 | 3 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #260 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.