Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
55
Total Reports
4
Deaths Reported
730.0%
Death Rate
5.2 yr
Avg Age at Report
Average weight at time of report: 13.5 kg (29.8 lbs)
Top Reported Reactions
Vomiting 12
Lack of efficacy - NOS 7
INEFFECTIVE, HEARTWORM LARVAE 4
Lethargy (see also Central nervous system depression in Neurological) 4
Anorexia 3
Seizure NOS 3
Dilated pupils 3
Not drinking 3
Behavioural disorder NOS 3
Lack of efficacy (tapeworm) 3
Diarrhoea 3
Shaking 3
Death 2
Anaemia NOS 2
Anaphylactoid reaction 2
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 5
Pyrantel Pamoate;Sarolaner 5
Milbemycin Oxime + Praziquantel 4
Fluralaner 13.64% 12-Week Chew 4
Milbemycin Oxime + Spinosad 3
Moxidectin 3
Fluralaner Chew Tablets 3
Trilostane 3
Ivermectin, Pyrantel 2
Ivermectin + Pyrantel Pamoate 2
Acepromazine 2
Isoflurane 2
Maropitant Citrate 2
Genta/Momet/Clotrim Ear Oint 2
Fenbendazole 1
Outcome Breakdown
Ongoing
16 (31.4%)
Recovered/Normal
15 (29.4%)
Outcome Unknown
13 (25.5%)
Recovered with Sequela
3 (5.9%)
Died
2 (3.9%)
Euthanized
2 (3.9%)
Gender Distribution
Male 35 (63.6%)
Female 19 (34.5%)
Unknown 1 (1.8%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 2 | |
| 2011 | 1 | |
| 2012 | 3 | |
| 2013 | 4 | |
| 2014 | 1 | |
| 2015 | 2 | |
| 2016 | 2 | |
| 2017 | 3 | |
| 2018 | 6 | |
| 2019 | 4 | |
| 2020 | 3 | |
| 2021 | 4 | |
| 2022 | 6 | |
| 2023 | 6 | |
| 2024 | 7 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #265 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.