Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
64
Total Reports
1
Deaths Reported
160.0%
Death Rate
6.6 yr
Avg Age at Report
Average weight at time of report: 22.0 kg (48.5 lbs)
Top Reported Reactions
Vomiting 18
Diarrhoea 8
Anorexia 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Behavioural disorder NOS 5
Emesis 5
INEFFECTIVE, HOOKS 5
Lack of efficacy - NOS 4
Weight loss 3
Lack of efficacy (endoparasite) - hookworm 3
Other abnormal test result NOS 3
Overdose 3
Hypoalbuminaemia 3
Pruritus 3
Lack of efficacy (ectoparasite) - flea 3
Most Referenced Drugs
Milbemycin Oxime + Spinosad 10
Afoxolaner 9
Ivermectin + Pyrantel As Pamoate Salt 8
Trilostane 7
Spinosad 6
Fluralaner Chew Tablets 4
Milbemycin Oxime, Lufenuron 3
Fluralaner 13.64% 12-Week Chew 3
Cyclosporine 2
Ivermectin, Pyrantel 2
Ivermectin + Pyrantel Pamoate 2
Lufenuron + Milbemycin Oxime 2
Isoflurane 2
Imidacloprid + Moxidectin 2
Flumethrin-Imidacloprid 2
Outcome Breakdown
Recovered/Normal
35 (59.3%)
Outcome Unknown
17 (28.8%)
Ongoing
6 (10.2%)
Euthanized
1 (1.7%)
Gender Distribution
Female 36 (56.3%)
Male 26 (40.6%)
Unknown 2 (3.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 5 | |
| 2011 | 2 | |
| 2012 | 3 | |
| 2013 | 4 | |
| 2014 | 6 | |
| 2015 | 7 | |
| 2016 | 10 | |
| 2017 | 1 | |
| 2018 | 8 | |
| 2019 | 5 | |
| 2020 | 2 | |
| 2021 | 4 | |
| 2022 | 1 | |
| 2023 | 2 | |
| 2024 | 2 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #256 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.