Wolf Hybrid

34 adverse event reports submitted to the FDA

Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your other canids.
34
Total Reports
1
Deaths Reported
290.0%
Death Rate
5.0 yr
Avg Age at Report
Average weight at time of report: 36.9 kg (81.4 lbs)

Top Reported Reactions

Vomiting 10
Lethargy (see also Central nervous system depression in 'Neurological') 4
Lack of efficacy (endoparasite) - heartworm 4
UNPALATABLE 3
Laboured breathing 3
Emesis 3
Skin lesion NOS 2
Weakness 2
Depression 2
Itching 2
Lack of efficacy - NOS 2
Hypoproteinaemia 2
Lack of efficacy (ectoparasite) - tick NOS 2
Reddening of the skin 2
Uncoded sign 1

Most Referenced Drugs

Spinosad 6
Milbemycin Oxime + Spinosad 5
Ivermectin + Pyrantel As Pamoate Salt 5
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Afoxolaner 3
Bedinvetmab 3
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 2
Ivermectin 2
Pyrantel Pamoate;Sarolaner 2
Melarsomine Dihydrocloride Injectable 25Mg/Ml 1
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 1
Deracoxib 1
Amoxicillin 1
Tramadol 1
Bifidobacterium/Enterococcus/Lactobacillus Supplement 1

Outcome Breakdown

Recovered/Normal
14 (41.2%)
Outcome Unknown
12 (35.3%)
Ongoing
5 (14.7%)
Recovered with Sequela
2 (5.9%)
Euthanized
1 (2.9%)

Gender Distribution

Male 23 (67.6%)
Female 11 (32.4%)

Reports by Year

Year Reports Trend
2011 2
2012 2
2013 4
2014 3
2015 7
2017 2
2018 3
2019 3
2020 1
2024 4
2025 3

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #304 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.