Total Reports
34
FDA CVM filings
FDA CVM · 2025 release 34 reports on file
Wolf Hybrid - FDA Adverse Event Profile
Adverse-event records for Wolf Hybrid (Other Canids) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Wolf Hybrid's FDA record: #304 most-reported other canids breed, 34 total reports, 2.9% death-coded (1 reports).
- #304
- most-reported other canids breed
- 2.9%
- death-coded report share
- 10
- Vomiting - top reaction
- 5.0 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
1
of 34 reports
Death Rate
2.9%
death-coded share
Avg Age at Report
5.0 yr
36.9 kg avg weight
Death-Coded Outcome Share
Wolf Hybrid death-coded reports 2.9%
Cross-breed median
2.9% of 34 wolf hybrid reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 36.9 kg (81.4 lbs)
Top Reported Reactions
Vomiting 10
Lethargy (see also Central nervous system depression in 'Neurological') 4
Lack of efficacy (endoparasite) - heartworm 4
UNPALATABLE 3
Laboured breathing 3
Most Referenced Drugs
Spinosad 6
Milbemycin Oxime + Spinosad 5
Ivermectin + Pyrantel As Pamoate Salt 5
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Afoxolaner 3
Outcome Breakdown
Recovered/Normal
14 (41.2%)
Outcome Unknown
12 (35.3%)
Ongoing
5 (14.7%)
Recovered with Sequela
2 (5.9%)
Euthanized
1 (2.9%)
Gender Distribution
Male 23 (67.6%)
Female 11 (32.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 2 | |
| 2012 | 2 | |
| 2013 | 4 | |
| 2014 | 3 | |
| 2015 | 7 | |
| 2017 | 2 | |
| 2018 | 3 | |
| 2019 | 3 | |
| 2020 | 1 | |
| 2024 | 4 | |
| 2025 | 3 | |
Wolf Hybrid Pet Health Insights
Wolf Hybrid accounts for 34 FDA adverse event reports, ranking #304 by volume among other canids breeds, with 1 reports (2.9%) coded as a death outcome. Mean age at report: 5.0 years, average weight 36.9 kg (81.4 lbs).
Top reported signs: Vomiting (10), Lethargy (see also Central nervous system depression in 'Neurological') (4), Lack of efficacy (endoparasite) - heartworm (4). Most-referenced drug: Spinosad (6 reports), followed by Milbemycin Oxime + Spinosad (5) and Ivermectin + Pyrantel As Pamoate Salt (5).
Outcome coding on 34 status-recorded reports is dominated by Recovered/Normal (41.2%). Annual submissions ranged 2,011-2,025 across 11 years on file.
Frequently Asked Questions
How many FDA adverse event reports involve Wolf Hybrid? ▼
There are 34 adverse event reports involving Wolf Hybrid in the FDA database, with 1 reports involving death (2.9% death rate). Wolf Hybrid ranks #304 by report volume.
What are the most common adverse reactions reported for Wolf Hybrid? ▼
The most commonly reported adverse reactions for Wolf Hybrid are Vomiting (10 reports), Lethargy (see also Central nervous system depression in 'Neurological') (4 reports), Lack of efficacy (endoparasite) - heartworm (4 reports), UNPALATABLE (3 reports), Laboured breathing (3 reports).
What drugs are most frequently associated with Wolf Hybrid adverse events? ▼
The drugs most frequently referenced in Wolf Hybrid adverse event reports are Spinosad (6 reports), Milbemycin Oxime + Spinosad (5 reports), Ivermectin + Pyrantel As Pamoate Salt (5 reports), Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg (3 reports), Afoxolaner (3 reports).
What is the average age of Wolf Hybrid in adverse event reports? ▼
The average age of Wolf Hybrid at the time of adverse event reports is 5.0 years, with an average weight of 36.9 kg (81.4 lbs).
Does a high number of adverse event reports mean Wolf Hybrid is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Wolf Hybrid safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.