Total Reports
35
Below-median volume
Breed profile · FDA CVM July 2026 extract
Wolf Hybrid adverse-event record
Adverse-event filings for Wolf Hybrid (Other Canids) in the FDA Center for Veterinary Medicine openFDA extract. Browse other canids breeds, reactions, and outcomes below.
- #307 of 510
- by report volume (all breeds)
- 35
- FDA CVM reports on file
- 2.9%
- death-coded share of reports
- 10
- Vomiting - top reaction
How the 35 reports break down
By recorded gender -- every report on file for Wolf Hybrid, no filtering.
Annual report volume
Data updated September 2026
The verdict
According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Wolf Hybrid ranks #306 of 510 by total reports (35). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).
- 93,675
- Retriever - Labrador reports (#1)
- 99.0%
- Atlantic Salmon (Salmo salar) death share (#1)
- #306
- This breed, reports of 510
Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.
Release-over-release change
What changed in the latest FDA data snapshot
PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Wolf Hybrid has 35 reports now versus 35 in that prior snapshot: 0 the same number of (0.0%).
- Report change
- +0
- Death-coded reports
- +0
- Death-coded share
- +0.0 pts
This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.
Subscribe to Wolf Hybrid changesDeaths Reported
1
of 35 reports
Death-coded share of reports
2.9%
2.9% death-coded
Avg Age at Report
5.2 yr
37.3 kg avg weight
Death-Coded Outcome Share
Wolf Hybrid death-coded reports 2.9%
Cross-breed median
2.9% of 35 wolf hybrid reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 37.3 kg (82.2 lbs)
Top Reported Reactions
Vomiting 10
Lethargy (see also Central nervous system depression in 'Neurological') 4
Lack of efficacy (endoparasite) - heartworm 4
UNPALATABLE 3
Laboured breathing 3
Most Referenced Drugs
Spinosad 6
Milbemycin Oxime + Spinosad 5
Ivermectin + Pyrantel As Pamoate Salt 5
Bedinvetmab 4
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Outcome Breakdown
Recovered/Normal
14 (40.0%)
Outcome Unknown
12 (34.3%)
Ongoing
6 (17.1%)
Recovered with Sequela
2 (5.7%)
Euthanized
1 (2.9%)
Gender Distribution
Male 24 (68.6%)
Female 11 (31.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 2 | |
| 2012 | 2 | |
| 2013 | 4 | |
| 2014 | 3 | |
| 2015 | 7 | |
| 2017 | 2 | |
| 2018 | 3 | |
| 2019 | 3 | |
| 2020 | 1 | |
| 2024 | 4 | |
| 2025 | 4 | |
Wolf Hybrid: low death-coded share in the FDA CVM extract
Signature read: Wolf Hybrid's 2.9% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Wolf Hybrid sits at #307 of 510 by report volume among all breeds and #1 of 1 among other canids breeds, with 35 reports and 1 (2.9%) death-coded. Mean age at report: 5.2 years, average weight 37.3 kg (82.2 lbs).
Top reported signs: Vomiting (10), Lethargy (see also Central nervous system depression in 'Neurological') (4), Lack of efficacy (endoparasite) - heartworm (4). Most-referenced drug: Spinosad (6 reports), followed by Milbemycin Oxime + Spinosad (5) and Ivermectin + Pyrantel As Pamoate Salt (5).
Outcome coding on 35 status-recorded reports is dominated by Recovered/Normal (40.0%). Annual submissions ranged 1-2,025 across 11 years on file.
Nationwide breeds with similar profiles
Two openFDA-derived peer sets for Wolf Hybrid, both outside the Other Canids family so the neighborhoods are not species containment (the similar-volume list above stays within species).
Similar average weight
Nearest other-species breeds by reported average weight (37.3 kg here).
What to do with this other canids
- Compare Wolf Hybrid's report volume and death-coded share against similar-volume breeds nationwide. See similar breeds
- Read how death-coded share differs from a mortality rate before drawing conclusions. Breed-specific risks guide
- Browse every other canids breed we track for comparison. All other canids breeds
A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.
Frequently Asked Questions
How many FDA adverse event reports involve Wolf Hybrid? ▼
There are 35 adverse event reports involving Wolf Hybrid in the FDA database, of which 1 were death-coded (2.9% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Wolf Hybrid ranks #307 of 510 by report volume among all breeds PlainBreed indexes (#1 of 1 among other canids breeds).
Where does Wolf Hybrid sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Wolf Hybrid is #307 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Other Canids, it is #1 of 1. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Wolf Hybrid? ▼
The most commonly reported adverse reactions for Wolf Hybrid are Vomiting (10 reports), Lethargy (see also Central nervous system depression in 'Neurological') (4 reports), Lack of efficacy (endoparasite) - heartworm (4 reports), UNPALATABLE (3 reports), Laboured breathing (3 reports).
What drugs are most frequently associated with Wolf Hybrid adverse events? ▼
The drugs most frequently referenced in Wolf Hybrid adverse event reports are Spinosad (6 reports), Milbemycin Oxime + Spinosad (5 reports), Ivermectin + Pyrantel As Pamoate Salt (5 reports), Bedinvetmab (4 reports), Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg (3 reports).
What is the average age of Wolf Hybrid in adverse event reports? ▼
The average age of Wolf Hybrid at the time of adverse event reports is 5.2 years, with an average weight of 37.3 kg (82.2 lbs).
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
openFDA Animal & Veterinary Adverse Events (FDA CVM) for Wolf Hybrid (Other Canids), extract as of July 2026 extract. 35 reports · 1 death-coded (2.9% of reports, not a mortality rate) · #307 of 510 by volume.
Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →