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2026 FDA CVM data 468 reports on file official source

Pointing Dog - German Wire-haired — FDA Adverse Event Profile

Adverse-event records and label data for Pointing Dog - German Wire-haired (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 46 34.5 23 11.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Pointing Dog - German Wire-haired drawn from FDA CVM filings.

Pointing Dog - German Wire-haired (Dog) has 468 FDA adverse event reports on record, with 19 deaths reported (410.0% death rate) — ranking #142 by report volume. The most frequently reported reaction is Vomiting (74 cases). The top associated drug is Ivermectin + Pyrantel As Pamoate Salt. Average age at report: 5.0 years.

Total Reports

468

FDA CVM filings

Deaths Reported

19

of 468 reports

Death Rate

410.0%

death-coded share

Avg Age at Report

5.0 yr

26.8 kg avg weight

Death-Coded Outcome Share

Pointing Dog - German Wire-haired death-coded reports 100.0%
Database median

410.0% of 468 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 26.8 kg (59.1 lbs)

Top Reported Reactions

Vomiting 74
Lack of efficacy (endoparasite) - heartworm 61
Lack of efficacy (endoparasite) - hookworm 46
Digestive tract disorder NOS 30
Lack of efficacy (ectoparasite) - tick NOS 27
INEFFECTIVE, HEARTWORM LARVAE 26
Diarrhoea 19
Lack of efficacy (bacteria) - Borrelia 19
Lack of efficacy (bacteria) - NOS 18
INEFFECTIVE, ASCARIDS NOS 17
Lethargy (see also Central nervous system depression in 'Neurological') 16
Lack of efficacy (endoparasite) - roundworm NOS 16
Lack of efficacy - NOS 15
Seizure NOS 12
Emesis 12

Most Referenced Drugs

Ivermectin + Pyrantel As Pamoate Salt 97
Milbemycin Oxime + Praziquantel 43
Afoxolaner 42
Pyrantel Pamoate;Sarolaner 41
Moxidectin 35
Milbemycin Oxime + Spinosad 29
Fluralaner Chew Tablets 18
Fluralaner 13.64% 12-Week Chew 18
Lotilaner 14
Carprofen 12
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 11
Oclacitinib Maleate 11
Sarolaner 11
Lufenuron + Milbemycin Oxime 9
Bedinvetmab 9

Outcome Breakdown

Outcome Unknown
162 (35.3%)
Ongoing
150 (32.7%)
Recovered/Normal
106 (23.1%)
Recovered with Sequela
22 (4.8%)
Euthanized
11 (2.4%)
Died
8 (1.7%)

Gender Distribution

Male 256 (54.7%)
Female 206 (44.0%)
Unknown 4 (0.9%)
Mixed 2 (0.4%)

Reports by Year

Year Reports Trend
2010 2
2011 8
2012 12
2013 19
2014 16
2015 27
2016 43
2017 30
2018 30
2019 45
2020 38
2021 41
2022 41
2023 41
2024 46
2025 29
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Pointing Dog - German Wire-haired sits in the registered size-class taxonomy. Average reported weight: 26.8 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Pointing Dog - German Wire-haired Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Pointing Dog - German Wire-haired accounts for 468 submitted reports and currently ranks #142 by report volume within the dog population. Of those reports, 19 involved a death outcome — a 410.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.0 years, with an average recorded body weight of 26.8 kg (59.1 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Pointing Dog - German Wire-haired are Vomiting (74 reports), Lack of efficacy (endoparasite) - heartworm (61 reports), Lack of efficacy (endoparasite) - hookworm (46 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Ivermectin + Pyrantel As Pamoate Salt appears in 97 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Praziquantel (43) and Afoxolaner (42). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 459 reports with a recorded status is dominated by Outcome Unknown (35.3% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Pointing Dog - German Wire-haired Adverse Event Data

Pointing Dog - German Wire-haired has 468 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.

The 410.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Ivermectin + Pyrantel As Pamoate Salt, appearing in 97 reports. This may indicate widespread use of the medication rather than a specific safety concern for Pointing Dog - German Wire-haired.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Pointing Dog - German Wire-haired?
There are 468 adverse event reports involving Pointing Dog - German Wire-haired in the FDA database, with 19 reports involving death (410.0% death rate). Pointing Dog - German Wire-haired ranks #142 by report volume.
What are the most common adverse reactions reported for Pointing Dog - German Wire-haired?
The most commonly reported adverse reactions for Pointing Dog - German Wire-haired are Vomiting (74 reports), Lack of efficacy (endoparasite) - heartworm (61 reports), Lack of efficacy (endoparasite) - hookworm (46 reports), Digestive tract disorder NOS (30 reports), Lack of efficacy (ectoparasite) - tick NOS (27 reports).
What drugs are most frequently associated with Pointing Dog - German Wire-haired adverse events?
The drugs most frequently referenced in Pointing Dog - German Wire-haired adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (97 reports), Milbemycin Oxime + Praziquantel (43 reports), Afoxolaner (42 reports), Pyrantel Pamoate;Sarolaner (41 reports), Moxidectin (35 reports).
What is the average age of Pointing Dog - German Wire-haired in adverse event reports?
The average age of Pointing Dog - German Wire-haired at the time of adverse event reports is 5.0 years, with an average weight of 26.8 kg (59.1 lbs).
Does a high number of adverse event reports mean Pointing Dog - German Wire-haired is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Pointing Dog - German Wire-haired safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Pointing Dog - German Wire-haired ranks #142 by total report volume. Death rate (410.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial