Total Reports
69
FDA CVM filings
Dog /
FDA CVM · 2025 release 69 reports on file
Carolina Dog - FDA Adverse Event Profile
Adverse-event records for Carolina Dog (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Carolina Dog is #249 by FDA report volume; 7.2% of its 69 reports (5) were death-coded.
- #249
- most-reported dog breed
- 7.2%
- death-coded report share
- 15
- Lack of efficacy (endoparasite) - heartworm - top reaction
- 5.7 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
5
of 69 reports
Death Rate
7.2%
death-coded share
Avg Age at Report
5.7 yr
23.4 kg avg weight
Death-Coded Outcome Share
Carolina Dog death-coded reports 7.2%
Cross-breed median
7.2% of 69 carolina dog reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 23.4 kg (51.6 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 15
Vomiting 11
Diarrhoea 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Ataxia 5
Most Referenced Drugs
Pyrantel Pamoate;Sarolaner 16
Milbemycin Oxime + Spinosad 9
Moxidectin 9
Milbemycin Oxime + Praziquantel 8
Ivermectin + Pyrantel As Pamoate Salt 8
Outcome Breakdown
Ongoing
29 (42.0%)
Outcome Unknown
22 (31.9%)
Recovered/Normal
12 (17.4%)
Euthanized
3 (4.3%)
Died
2 (2.9%)
Recovered with Sequela
1 (1.4%)
Gender Distribution
Female 42 (60.9%)
Male 25 (36.2%)
Mixed 1 (1.4%)
Unknown 1 (1.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 2 | |
| 2014 | 3 | |
| 2015 | 3 | |
| 2016 | 3 | |
| 2017 | 3 | |
| 2018 | 5 | |
| 2019 | 7 | |
| 2020 | 8 | |
| 2021 | 7 | |
| 2022 | 3 | |
| 2023 | 9 | |
| 2024 | 7 | |
| 2025 | 8 | |
Carolina Dog Pet Health Insights
Carolina Dog accounts for 69 FDA adverse event reports, ranking #249 by volume among dog breeds, with 5 reports (7.2%) coded as a death outcome. Mean age at report: 5.7 years, average weight 23.4 kg (51.6 lbs).
Top reported signs: Lack of efficacy (endoparasite) - heartworm (15), Vomiting (11), Diarrhoea (6). Most-referenced drug: Pyrantel Pamoate;Sarolaner (16 reports), followed by Milbemycin Oxime + Spinosad (9) and Moxidectin (9).
Outcome coding on 69 status-recorded reports is dominated by Ongoing (42.0%). Annual submissions ranged 2,012-2,025 across 14 years on file.
Dog Breeds With a Similar Report Volume
Spaniel - Clumber
69 reports · 1.4% death rate
Spaniel - Field
69 reports · 2.9% death rate
Mastiff - Neapolitan
67 reports · 7.5% death rate
Terrier - Kerry Blue
71 reports · 7.0% death rate
Chinese Crested Dog – Powder Puff with veil coat
65 reports · 3.1% death rate
Chinese Crested Dog – Hairless
64 reports · 3.1% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Carolina Dog? ▼
There are 69 adverse event reports involving Carolina Dog in the FDA database, with 5 reports involving death (7.2% death rate). Carolina Dog ranks #249 by report volume.
What are the most common adverse reactions reported for Carolina Dog? ▼
The most commonly reported adverse reactions for Carolina Dog are Lack of efficacy (endoparasite) - heartworm (15 reports), Vomiting (11 reports), Diarrhoea (6 reports), Lethargy (see also Central nervous system depression in 'Neurological') (5 reports), Ataxia (5 reports).
What drugs are most frequently associated with Carolina Dog adverse events? ▼
The drugs most frequently referenced in Carolina Dog adverse event reports are Pyrantel Pamoate;Sarolaner (16 reports), Milbemycin Oxime + Spinosad (9 reports), Moxidectin (9 reports), Milbemycin Oxime + Praziquantel (8 reports), Ivermectin + Pyrantel As Pamoate Salt (8 reports).
What is the average age of Carolina Dog in adverse event reports? ▼
The average age of Carolina Dog at the time of adverse event reports is 5.7 years, with an average weight of 23.4 kg (51.6 lbs).
Does a high number of adverse event reports mean Carolina Dog is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Carolina Dog safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.