Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
69
Total Reports
2
Deaths Reported
290.0%
Death Rate
6.3 yr
Avg Age at Report
Average weight at time of report: 18.7 kg (41.2 lbs)
Top Reported Reactions
Vomiting 13
Digestive tract disorder NOS 10
Lack of efficacy (endoparasite) - hookworm 9
Lethargy (see also Central nervous system depression in 'Neurological') 9
Lack of efficacy - NOS 6
Diarrhoea 6
INEFFECTIVE, ASCARIDS NOS 5
Emesis 5
Other abnormal test result NOS 4
Seizure NOS 4
Inappetence 3
Elevated alanine aminotransferase (ALT) 3
Elevated serum alkaline phosphatase (SAP) 3
Anaemia NOS 3
Anorexia 3
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 11
Afoxolaner 6
Fluralaner Chew Tablets 5
Milbemycin Oxime + Spinosad 4
Milbemycin Oxime + Praziquantel 4
Milbemycin 3
Carprofen 3
Pyrantel Pamoate;Sarolaner 3
Spinosad 2
Ivermectin 136Mcg, Pyrantel Pamoate 114Mg, Praziquantel 114Mg 2
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 2
Imidacloprid + Moxidectin 2
Oclacitinib Maleate 2
Milbemycin Oxime, Lufenuron 2
Thyroid Medication (Unknown) 2
Outcome Breakdown
Outcome Unknown
30 (47.6%)
Recovered/Normal
19 (30.2%)
Ongoing
11 (17.5%)
Died
2 (3.2%)
Recovered with Sequela
1 (1.6%)
Gender Distribution
Female 39 (56.5%)
Male 30 (43.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 3 | |
| 2011 | 2 | |
| 2012 | 6 | |
| 2013 | 7 | |
| 2014 | 11 | |
| 2015 | 4 | |
| 2016 | 7 | |
| 2017 | 4 | |
| 2018 | 6 | |
| 2019 | 4 | |
| 2020 | 1 | |
| 2021 | 2 | |
| 2022 | 5 | |
| 2023 | 2 | |
| 2024 | 1 | |
| 2025 | 4 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #247 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.