Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
69
Total Reports
1
Deaths Reported
140.0%
Death Rate
4.9 yr
Avg Age at Report
Average weight at time of report: 28.5 kg (62.8 lbs)
Top Reported Reactions
Vomiting 18
Lethargy (see also Central nervous system depression in 'Neurological') 15
Diarrhoea 14
Anorexia 6
Emesis 6
Lack of efficacy - NOS 5
Bloody diarrhoea 5
Overdose 4
Lack of efficacy (endoparasite) - hookworm 3
Behavioural disorder NOS 3
Lack of efficacy (ectoparasite) - flea 3
Inappetence 3
Underdose 3
Digestive tract disorder NOS 2
Depression 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 18
Oclacitinib Maleate 7
Ivermectin + Pyrantel As Pamoate Salt 5
Afoxolaner 4
Betamethasone + Florfenicol + Terbinafine 3
Milbemycin Oxime + Praziquantel 3
Lotilaner 3
Spinosad 2
Deracoxib 2
Imidacloprid + Moxidectin 2
Moxidectin 2
Levothyroxine Sodium 2
Fluralaner Chew Tablets 2
Carprofen 2
Prednisone 2
Outcome Breakdown
Recovered/Normal
31 (47.0%)
Outcome Unknown
20 (30.3%)
Ongoing
12 (18.2%)
Recovered with Sequela
2 (3.0%)
Died
1 (1.5%)
Gender Distribution
Male 39 (56.5%)
Female 24 (34.8%)
Unknown 6 (8.7%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 5 | |
| 2012 | 12 | |
| 2013 | 4 | |
| 2014 | 4 | |
| 2015 | 7 | |
| 2016 | 4 | |
| 2017 | 5 | |
| 2018 | 5 | |
| 2019 | 2 | |
| 2020 | 5 | |
| 2021 | 4 | |
| 2022 | 1 | |
| 2023 | 2 | |
| 2024 | 4 | |
| 2025 | 5 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #248 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.