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2026 FDA CVM data 1,083 reports on file official source

Akita — FDA Adverse Event Profile

Adverse-event records and label data for Akita (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 74 55.5 37 18.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Akita drawn from FDA CVM filings.

Akita (Dog) has 1,083 FDA adverse event reports on record, with 55 deaths reported (510.0% death rate) — ranking #107 by report volume. The most frequently reported reaction is Vomiting (178 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 5.4 years.

Total Reports

1,083

FDA CVM filings

Deaths Reported

55

of 1,083 reports

Death Rate

510.0%

death-coded share

Avg Age at Report

5.4 yr

37.3 kg avg weight

Death-Coded Outcome Share

Akita death-coded reports 100.0%
Database median

510.0% of 1,083 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 37.3 kg (82.2 lbs)

Top Reported Reactions

Vomiting 178
Lethargy (see also Central nervous system depression in 'Neurological') 126
Emesis 92
Diarrhoea 79
INEFFECTIVE, HEARTWORM LARVAE 77
Lack of efficacy (endoparasite) - heartworm 65
Lack of efficacy - NOS 47
Lack of efficacy (ectoparasite) - flea 46
Seizure NOS 45
Other abnormal test result NOS 42
Anorexia 41
Behavioural disorder NOS 41
Ataxia 31
Lack of efficacy (bacteria) - Borrelia 30
Panting 29

Most Referenced Drugs

Milbemycin Oxime + Spinosad 217
Ivermectin + Pyrantel As Pamoate Salt 98
Afoxolaner 83
Spinosad 79
Pyrantel Pamoate;Sarolaner 58
Carprofen 44
Fluralaner Chew Tablets 44
Oclacitinib Maleate 41
Bedinvetmab 41
Moxidectin 34
Milbemycin Oxime + Praziquantel 33
Fluralaner 13.64% 12-Week Chew 27
Selamectin 23
Grapiprant 20
Prednisone 19

Outcome Breakdown

Recovered/Normal
331 (32.6%)
Outcome Unknown
311 (30.6%)
Ongoing
266 (26.2%)
Recovered with Sequela
52 (5.1%)
Died
34 (3.3%)
Euthanized
21 (2.1%)

Gender Distribution

Male 566 (52.3%)
Female 493 (45.5%)
Unknown 17 (1.6%)
Mixed 7 (0.6%)

Reports by Year

Year Reports Trend
2010 34
2011 65
2012 90
2013 77
2014 92
2015 94
2016 85
2017 75
2018 74
2019 59
2020 49
2021 52
2022 62
2023 58
2024 74
2025 43
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Akita sits in the registered size-class taxonomy. Average reported weight: 37.3 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Akita Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Akita accounts for 1,083 submitted reports and currently ranks #107 by report volume within the dog population. Of those reports, 55 involved a death outcome — a 510.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.4 years, with an average recorded body weight of 37.3 kg (82.2 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Akita are Vomiting (178 reports), Lethargy (see also Central nervous system depression in 'Neurological') (126 reports), Emesis (92 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 217 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (98) and Afoxolaner (83). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 1,015 reports with a recorded status is dominated by Recovered/Normal (32.6% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Akita Adverse Event Data

Akita has a moderate volume of adverse event reports (1,083). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 510.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 217 reports. This may indicate widespread use of the medication rather than a specific safety concern for Akita.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Akita?
There are 1,083 adverse event reports involving Akita in the FDA database, with 55 reports involving death (510.0% death rate). Akita ranks #107 by report volume.
What are the most common adverse reactions reported for Akita?
The most commonly reported adverse reactions for Akita are Vomiting (178 reports), Lethargy (see also Central nervous system depression in 'Neurological') (126 reports), Emesis (92 reports), Diarrhoea (79 reports), INEFFECTIVE, HEARTWORM LARVAE (77 reports).
What drugs are most frequently associated with Akita adverse events?
The drugs most frequently referenced in Akita adverse event reports are Milbemycin Oxime + Spinosad (217 reports), Ivermectin + Pyrantel As Pamoate Salt (98 reports), Afoxolaner (83 reports), Spinosad (79 reports), Pyrantel Pamoate;Sarolaner (58 reports).
What is the average age of Akita in adverse event reports?
The average age of Akita at the time of adverse event reports is 5.4 years, with an average weight of 37.3 kg (82.2 lbs).
Does a high number of adverse event reports mean Akita is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Akita safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Akita ranks #107 by total report volume. Death rate (510.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial