Total Reports
1,124
FDA CVM filings
Dog /
FDA CVM · 2025 release 1,124 reports on file
Spitz - American Eskimo Dog - FDA Adverse Event Profile
Adverse-event records for Spitz - American Eskimo Dog (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 1,124 reports on file, Spitz - American Eskimo Dog sits at #105 among dog breeds by volume; death-coded share is 4.6% (52 reports).
- #105
- most-reported dog breed
- 4.6%
- death-coded report share
- 274
- Vomiting - top reaction
- 7.2 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
52
of 1,124 reports
Death Rate
4.6%
death-coded share
Avg Age at Report
7.2 yr
11.6 kg avg weight
Death-Coded Outcome Share
Spitz - American Eskimo Dog death-coded reports 4.6%
Cross-breed median
4.6% of 1,124 spitz - american eskimo dog reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 11.6 kg (25.6 lbs)
Top Reported Reactions
Vomiting 274
Lethargy (see also Central nervous system depression in 'Neurological') 118
Diarrhoea 101
Emesis 101
Lack of efficacy (ectoparasite) - flea 74
Seizure NOS 68
Lack of efficacy - NOS 51
Lack of efficacy (endoparasite) - hookworm 47
Anorexia 47
Digestive tract disorder NOS 38
Behavioural disorder NOS 35
INEFFECTIVE, HEARTWORM LARVAE 31
Elevated blood urea nitrogen (BUN) 29
Ataxia 27
Emesis (multiple) 25
Most Referenced Drugs
Milbemycin Oxime + Spinosad 192
Spinosad 96
Afoxolaner 89
Ivermectin + Pyrantel As Pamoate Salt 83
Fluralaner Chew Tablets 53
Trilostane 45
Moxidectin 39
Carprofen 33
Sarolaner 33
Pyrantel Pamoate;Sarolaner 33
Milbemycin Oxime + Praziquantel 31
Fluralaner 13.64% 12-Week Chew 27
Bedinvetmab 22
Selamectin 21
Imidacloprid + Moxidectin 17
Outcome Breakdown
Recovered/Normal
389 (38.4%)
Outcome Unknown
328 (32.3%)
Ongoing
200 (19.7%)
Recovered with Sequela
45 (4.4%)
Died
26 (2.6%)
Euthanized
26 (2.6%)
Gender Distribution
Male 557 (49.6%)
Female 549 (48.8%)
Unknown 16 (1.4%)
Mixed 2 (0.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 66 | |
| 2011 | 74 | |
| 2012 | 91 | |
| 2013 | 97 | |
| 2014 | 93 | |
| 2015 | 95 | |
| 2016 | 80 | |
| 2017 | 78 | |
| 2018 | 69 | |
| 2019 | 82 | |
| 2020 | 78 | |
| 2021 | 54 | |
| 2022 | 35 | |
| 2023 | 43 | |
| 2024 | 59 | |
| 2025 | 30 | |
Spitz - American Eskimo Dog Pet Health Insights
Spitz - American Eskimo Dog accounts for 1,124 FDA adverse event reports, ranking #105 by volume among dog breeds, with 52 reports (4.6%) coded as a death outcome. Mean age at report: 7.2 years, average weight 11.6 kg (25.6 lbs).
Top reported signs: Vomiting (274), Lethargy (see also Central nervous system depression in 'Neurological') (118), Diarrhoea (101). Most-referenced drug: Milbemycin Oxime + Spinosad (192 reports), followed by Spinosad (96) and Afoxolaner (89).
Outcome coding on 1,014 status-recorded reports is dominated by Recovered/Normal (38.4%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Dachshund - Standard Long-haired
1,104 reports · 5.7% death rate
Akita
1,083 reports · 5.1% death rate
Retriever - Chesapeake Bay
1,051 reports · 2.9% death rate
Corgi - Welsh Cardigan
1,200 reports · 3.4% death rate
Coonhound (unspecified)
1,210 reports · 3.0% death rate
Setter - English
1,210 reports · 3.6% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Spitz - American Eskimo Dog? ▼
There are 1,124 adverse event reports involving Spitz - American Eskimo Dog in the FDA database, with 52 reports involving death (4.6% death rate). Spitz - American Eskimo Dog ranks #105 by report volume.
What are the most common adverse reactions reported for Spitz - American Eskimo Dog? ▼
The most commonly reported adverse reactions for Spitz - American Eskimo Dog are Vomiting (274 reports), Lethargy (see also Central nervous system depression in 'Neurological') (118 reports), Diarrhoea (101 reports), Emesis (101 reports), Lack of efficacy (ectoparasite) - flea (74 reports).
What drugs are most frequently associated with Spitz - American Eskimo Dog adverse events? ▼
The drugs most frequently referenced in Spitz - American Eskimo Dog adverse event reports are Milbemycin Oxime + Spinosad (192 reports), Spinosad (96 reports), Afoxolaner (89 reports), Ivermectin + Pyrantel As Pamoate Salt (83 reports), Fluralaner Chew Tablets (53 reports).
What is the average age of Spitz - American Eskimo Dog in adverse event reports? ▼
The average age of Spitz - American Eskimo Dog at the time of adverse event reports is 7.2 years, with an average weight of 11.6 kg (25.6 lbs).
Does a high number of adverse event reports mean Spitz - American Eskimo Dog is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Spitz - American Eskimo Dog safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.