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2026 FDA CVM data 1,051 reports on file official source

Retriever - Chesapeake Bay — FDA Adverse Event Profile

Adverse-event records and label data for Retriever - Chesapeake Bay (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 79 59.25 39.5 19.75 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Retriever - Chesapeake Bay drawn from FDA CVM filings.

Retriever - Chesapeake Bay (Dog) has 1,051 FDA adverse event reports on record, with 31 deaths reported (290.0% death rate) — ranking #108 by report volume. The most frequently reported reaction is INEFFECTIVE, HEARTWORM LARVAE (166 cases). The top associated drug is Ivermectin + Pyrantel As Pamoate Salt. Average age at report: 5.3 years.

Total Reports

1,051

FDA CVM filings

Deaths Reported

31

of 1,051 reports

Death Rate

290.0%

death-coded share

Avg Age at Report

5.3 yr

35.5 kg avg weight

Death-Coded Outcome Share

Retriever - Chesapeake Bay death-coded reports 100.0%
Database median

290.0% of 1,051 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 35.5 kg (78.3 lbs)

Top Reported Reactions

INEFFECTIVE, HEARTWORM LARVAE 166
Lack of efficacy (endoparasite) - heartworm 150
Vomiting 136
Lack of efficacy - NOS 81
Lack of efficacy (endoparasite) - hookworm 73
Diarrhoea 60
Lethargy (see also Central nervous system depression in 'Neurological') 53
Seizure NOS 44
INEFFECTIVE, ASCARIDS NOS 42
Digestive tract disorder NOS 35
Cardiac disorder NOS 35
Anorexia 32
Emesis 28
Lack of efficacy (ectoparasite) - flea 25
Other abnormal test result NOS 23

Most Referenced Drugs

Ivermectin + Pyrantel As Pamoate Salt 196
Milbemycin Oxime + Spinosad 151
Milbemycin Oxime + Praziquantel 84
Afoxolaner 60
Pyrantel Pamoate;Sarolaner 49
Moxidectin 47
Carprofen 41
Ivermectin, Pyrantel 35
Fluralaner Chew Tablets 35
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 29
Milbemycin 28
Bedinvetmab 28
Oclacitinib Maleate 26
Fluralaner 13.64% 12-Week Chew 25
Milbemycin Oxime 23

Outcome Breakdown

Outcome Unknown
356 (38.4%)
Ongoing
258 (27.8%)
Recovered/Normal
208 (22.4%)
Recovered with Sequela
75 (8.1%)
Euthanized
18 (1.9%)
Died
13 (1.4%)

Gender Distribution

Male 568 (54.0%)
Female 468 (44.5%)
Unknown 13 (1.2%)
Mixed 2 (0.2%)

Reports by Year

Year Reports Trend
2010 62
2011 70
2012 67
2013 56
2014 61
2015 62
2016 77
2017 79
2018 77
2019 67
2020 71
2021 72
2022 50
2023 59
2024 79
2025 42
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Retriever - Chesapeake Bay sits in the registered size-class taxonomy. Average reported weight: 35.5 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Retriever - Chesapeake Bay Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Retriever - Chesapeake Bay accounts for 1,051 submitted reports and currently ranks #108 by report volume within the dog population. Of those reports, 31 involved a death outcome — a 290.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.3 years, with an average recorded body weight of 35.5 kg (78.3 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Retriever - Chesapeake Bay are INEFFECTIVE, HEARTWORM LARVAE (166 reports), Lack of efficacy (endoparasite) - heartworm (150 reports), Vomiting (136 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Ivermectin + Pyrantel As Pamoate Salt appears in 196 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Spinosad (151) and Milbemycin Oxime + Praziquantel (84). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 928 reports with a recorded status is dominated by Outcome Unknown (38.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Retriever - Chesapeake Bay Adverse Event Data

Retriever - Chesapeake Bay has a moderate volume of adverse event reports (1,051). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 290.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Ivermectin + Pyrantel As Pamoate Salt, appearing in 196 reports. This may indicate widespread use of the medication rather than a specific safety concern for Retriever - Chesapeake Bay.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Retriever - Chesapeake Bay?
There are 1,051 adverse event reports involving Retriever - Chesapeake Bay in the FDA database, with 31 reports involving death (290.0% death rate). Retriever - Chesapeake Bay ranks #108 by report volume.
What are the most common adverse reactions reported for Retriever - Chesapeake Bay?
The most commonly reported adverse reactions for Retriever - Chesapeake Bay are INEFFECTIVE, HEARTWORM LARVAE (166 reports), Lack of efficacy (endoparasite) - heartworm (150 reports), Vomiting (136 reports), Lack of efficacy - NOS (81 reports), Lack of efficacy (endoparasite) - hookworm (73 reports).
What drugs are most frequently associated with Retriever - Chesapeake Bay adverse events?
The drugs most frequently referenced in Retriever - Chesapeake Bay adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (196 reports), Milbemycin Oxime + Spinosad (151 reports), Milbemycin Oxime + Praziquantel (84 reports), Afoxolaner (60 reports), Pyrantel Pamoate;Sarolaner (49 reports).
What is the average age of Retriever - Chesapeake Bay in adverse event reports?
The average age of Retriever - Chesapeake Bay at the time of adverse event reports is 5.3 years, with an average weight of 35.5 kg (78.3 lbs).
Does a high number of adverse event reports mean Retriever - Chesapeake Bay is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Retriever - Chesapeake Bay safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Retriever - Chesapeake Bay ranks #108 by total report volume. Death rate (290.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial