Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
84
Total Reports
3
Deaths Reported
360.0%
Death Rate
3.6 yr
Avg Age at Report
Average weight at time of report: 36.4 kg (80.3 lbs)
Top Reported Reactions
Vomiting 23
Diarrhoea 9
Emesis (multiple) 9
Lack of efficacy (ectoparasite) - flea 8
Lethargy (see also Central nervous system depression in 'Neurological') 7
Emesis 6
Lack of efficacy (endoparasite) - heartworm 6
Drooling 4
Not eating 4
Lethargy (see also Central nervous system depression in Neurological) 4
Lack of efficacy (endoparasite) - hookworm 3
Walking difficulty 3
Lack of efficacy (flea) 3
Lack of efficacy (ectoparasite) - tick NOS 3
Digestive tract disorder NOS 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 39
Fluralaner 13.64% 12-Week Chew 10
Spinosad 8
Ivermectin + Pyrantel As Pamoate Salt 6
Nitenpyram 3
Oclacitinib Maleate 3
Milbemycin/Lufenuron/Pzq Chew 3
Prednisone 3
Fluralaner Chew Tablets 2
Lotilaner 2
Imidacloprid 2
Milbemycin/Lufenuron Tablets 2
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 2
Ivermectin/Pyrantel Chew. Dog 272Mcg/227Mg 1
Bordetella Vaccine 1
Outcome Breakdown
Recovered/Normal
30 (35.7%)
Outcome Unknown
25 (29.8%)
Ongoing
23 (27.4%)
Recovered with Sequela
3 (3.6%)
Died
2 (2.4%)
Euthanized
1 (1.2%)
Gender Distribution
Female 42 (50.0%)
Male 41 (48.8%)
Unknown 1 (1.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 4 | |
| 2013 | 4 | |
| 2014 | 5 | |
| 2015 | 6 | |
| 2016 | 12 | |
| 2017 | 2 | |
| 2018 | 7 | |
| 2019 | 7 | |
| 2020 | 5 | |
| 2021 | 4 | |
| 2022 | 4 | |
| 2023 | 10 | |
| 2024 | 4 | |
| 2025 | 9 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #242 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.