Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
89
Total Reports
3
Deaths Reported
340.0%
Death Rate
5.5 yr
Avg Age at Report
Average weight at time of report: 6.3 kg (13.9 lbs)
Top Reported Reactions
Vomiting 23
Lethargy (see also Central nervous system depression in 'Neurological') 17
Emesis 13
Diarrhoea 10
Seizure NOS 7
Tremor 6
Shaking 6
Abnormal posture NOS 6
Lack of efficacy (endoparasite) - hookworm 5
Decreased appetite 5
Walking difficulty 4
Behavioural disorder NOS 4
Not eating 4
Lack of efficacy (ectoparasite) - flea 4
Lack of efficacy - NOS 4
Most Referenced Drugs
Fluralaner Chew Tablets 23
Milbemycin Oxime + Spinosad 22
Spinosad 13
Butorphanol Tartrate 4
Fluralaner 13.64% 12-Week Chew 4
Pyrantel Pamoate;Sarolaner 4
Cefovecin 3
Carprofen 2
Insulin Injectable Vial 2
Milbemycin/Lufenuron Tablets 2
Phenobarbital 1
Milbemycin Oxime 1
Ivermectin 1
Imidacloprid + Moxidectin 1
Selamectin 1
Outcome Breakdown
Recovered/Normal
44 (49.4%)
Ongoing
19 (21.3%)
Outcome Unknown
16 (18.0%)
Recovered with Sequela
7 (7.9%)
Died
3 (3.4%)
Gender Distribution
Female 46 (51.7%)
Male 41 (46.1%)
Unknown 2 (2.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 1 | |
| 2011 | 1 | |
| 2012 | 21 | |
| 2013 | 14 | |
| 2014 | 11 | |
| 2015 | 2 | |
| 2016 | 14 | |
| 2017 | 4 | |
| 2018 | 4 | |
| 2019 | 4 | |
| 2020 | 3 | |
| 2021 | 5 | |
| 2022 | 2 | |
| 2023 | 2 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #237 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.