Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
93
Total Reports
5
Deaths Reported
540.0%
Death Rate
8.7 yr
Avg Age at Report
Average weight at time of report: 8.2 kg (18.1 lbs)
Top Reported Reactions
Emesis 15
Vomiting 11
Lethargy (see also Central nervous system depression in 'Neurological') 8
Lack of efficacy (ectoparasite) - flea 7
Seizure NOS 5
Underdose 5
Bloody diarrhoea 4
Diarrhoea 4
Not eating 4
INEFFECTIVE, GLYCEMIC CONTROL 4
Lack of efficacy - NOS 4
Death by euthanasia 3
Weight loss 3
Lack of efficacy (flea) 3
INEFFECTIVE, CUSHINGS 3
Most Referenced Drugs
Trilostane 21
Milbemycin Oxime + Spinosad 18
Fluralaner Chew Tablets 14
Fluralaner 13.64% 12-Week Chew 8
Insulin Injectable Vial 4
Gabapentin 4
Pyrantel Pamoate;Sarolaner 4
Spinosad 3
Levothyroxine Sodium 2
Moxidectin 2
Milbemycin Oxime + Praziquantel 2
Fenbendazol Granules 2
Lotilaner 2
Estriol Tablets 2
Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg 1
Outcome Breakdown
Recovered/Normal
33 (35.5%)
Outcome Unknown
27 (29.0%)
Ongoing
25 (26.9%)
Euthanized
3 (3.2%)
Recovered with Sequela
3 (3.2%)
Died
2 (2.2%)
Gender Distribution
Female 55 (59.1%)
Male 38 (40.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 8 | |
| 2013 | 9 | |
| 2014 | 3 | |
| 2015 | 7 | |
| 2016 | 8 | |
| 2017 | 11 | |
| 2018 | 8 | |
| 2019 | 7 | |
| 2020 | 7 | |
| 2021 | 7 | |
| 2022 | 6 | |
| 2023 | 6 | |
| 2024 | 3 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #236 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.