Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
86
Total Reports
3
Deaths Reported
350.0%
Death Rate
5.4 yr
Avg Age at Report
Average weight at time of report: 23.4 kg (51.6 lbs)
Top Reported Reactions
Vomiting 12
Lack of efficacy (bacteria) - Borrelia 8
Seizure NOS 6
Lack of efficacy (endoparasite) - roundworm NOS 6
Lack of efficacy (ectoparasite) - tick NOS 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Diarrhoea 4
Lack of efficacy (endoparasite) - hookworm 4
Ataxia 3
Death by euthanasia 3
Emesis (multiple) 3
Lack of efficacy (endoparasite) - whipworm 3
Lack of efficacy (bacteria) - Anaplasma 3
Polydipsia 2
INEFFECTIVE, HEARTWORM LARVAE 2
Most Referenced Drugs
Pyrantel Pamoate;Sarolaner 27
Moxidectin 13
Sarolaner 10
Bedinvetmab 8
Milbemycin Oxime 5
Milbemycin Oxime + Spinosad 4
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 4
Carprofen 3
Maropitant Citrate 3
Fluralaner Chew Tablets 3
Anti-Il31 Mab Mcs Lot #1283563 3
Ivermectin + Pyrantel 3
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 3
Fluralaner 13.64% 12-Week Chew 3
Oclacitinib Maleate 2
Outcome Breakdown
Ongoing
51 (59.3%)
Outcome Unknown
17 (19.8%)
Recovered/Normal
15 (17.4%)
Euthanized
3 (3.5%)
Gender Distribution
Male 55 (64.0%)
Female 30 (34.9%)
Unknown 1 (1.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 3 | |
| 2014 | 3 | |
| 2016 | 2 | |
| 2017 | 5 | |
| 2018 | 6 | |
| 2019 | 10 | |
| 2020 | 3 | |
| 2021 | 10 | |
| 2022 | 3 | |
| 2023 | 11 | |
| 2024 | 16 | |
| 2025 | 13 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #240 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.