Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
84
Total Reports
5
Deaths Reported
600.0%
Death Rate
6.4 yr
Avg Age at Report
Average weight at time of report: 8.7 kg (19.2 lbs)
Top Reported Reactions
Vomiting 19
Lethargy (see also Central nervous system depression in 'Neurological') 14
Emesis 12
Seizure NOS 8
Diarrhoea 5
Behavioural disorder NOS 4
Lack of efficacy - NOS 4
Eye disorder NOS (for photophobia see 'neurological') 3
Shaking 3
Emesis (multiple) 3
Elevated liver enzymes 3
Deafness 3
Other abnormal test result NOS 3
Anorexia 3
Death 3
Most Referenced Drugs
Milbemycin Oxime + Spinosad 21
Spinosad 12
Oclacitinib Maleate 4
Fluralaner Chew Tablets 4
Milbemycin Oxime + Praziquantel 4
Cyclosporine A 3
Butorphanol Tartrate 3
Carprofen 3
Ivermectin + Pyrantel As Pamoate Salt 3
Trilostane 3
Sarolaner 3
Moxidectin 3
Maropitant Citrate 3
Metronidazole 2
Pimobendan 2
Outcome Breakdown
Recovered/Normal
37 (47.4%)
Outcome Unknown
16 (20.5%)
Ongoing
16 (20.5%)
Recovered with Sequela
4 (5.1%)
Died
3 (3.8%)
Euthanized
2 (2.6%)
Gender Distribution
Male 42 (50.0%)
Female 40 (47.6%)
Unknown 2 (2.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 1 | |
| 2011 | 7 | |
| 2012 | 6 | |
| 2013 | 13 | |
| 2014 | 9 | |
| 2015 | 8 | |
| 2016 | 3 | |
| 2017 | 6 | |
| 2018 | 4 | |
| 2019 | 7 | |
| 2020 | 7 | |
| 2021 | 2 | |
| 2022 | 2 | |
| 2023 | 2 | |
| 2024 | 3 | |
| 2025 | 4 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #241 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.