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Breed profile · FDA CVM July 2026 extract

Affenpinscher adverse-event record

Adverse-event filings for Affenpinscher (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#241 of 510
by report volume (all breeds)
88
FDA CVM reports on file
5.7%
death-coded share of reports
#110 of 275
by death-coded share (≥50 reports)

How the 88 reports break down

By recorded gender -- every report on file for Affenpinscher, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 8 6 4 2 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Affenpinscher drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Affenpinscher ranks #241 of 510 by total reports (88) and #110 of 275 by death-coded share (5.7%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#241
This breed, reports of 510
#110
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Affenpinscher has 88 reports now versus 88 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Affenpinscher changes

Total Reports

88

Above-median volume

Deaths Reported

5

of 88 reports

Death-coded share of reports

5.7%

Above-median death-coded share

Avg Age at Report

6.5 yr

8.5 kg avg weight

Death-Coded Outcome Share

Affenpinscher death-coded reports 5.7%
Cross-breed median

5.7% of 88 affenpinscher reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Affenpinscher's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

6% 60th percentile Higher share than 60% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Affenpinscher 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 8.5 kg (18.7 lbs)

Top Reported Reactions

Vomiting 19
Lethargy (see also Central nervous system depression in 'Neurological') 14
Emesis 12
Seizure NOS 8
Diarrhoea 7

Most Referenced Drugs

Milbemycin Oxime + Spinosad 21
Spinosad 12
Oclacitinib Maleate 4
Fluralaner Chew Tablets 4
Milbemycin Oxime + Praziquantel 4

Outcome Breakdown

Recovered/Normal
38 (46.3%)
Ongoing
19 (23.2%)
Outcome Unknown
16 (19.5%)
Recovered with Sequela
4 (4.9%)
Died
3 (3.7%)
Euthanized
2 (2.4%)

Gender Distribution

Male 43 (48.9%)
Female 43 (48.9%)
Unknown 2 (2.3%)

Reports by Year

Year Reports Trend
2010 1
2011 7
2012 6
2013 13
2014 9
2015 8
2016 3
2017 6
2018 4
2019 7
2020 7
2021 2
2022 2
2023 2
2024 3
2025 8

Affenpinscher FDA adverse-event insights

Signature read: death-coded share at 5.7% is the standout outcome stamp on Affenpinscher's FDA row. According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Affenpinscher sits at #241 of 510 by report volume among all breeds and #175 of 298 among dog breeds, with 88 reports and 5 (5.7%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #110 of 275. Mean age at report: 6.5 years, average weight 8.5 kg (18.7 lbs).

Top reported signs: Vomiting (19), Lethargy (see also Central nervous system depression in 'Neurological') (14), Emesis (12). Most-referenced drug: Milbemycin Oxime + Spinosad (21 reports), followed by Spinosad (12) and Oclacitinib Maleate (4).

Outcome coding on 82 status-recorded reports is dominated by Recovered/Normal (46.3%). Annual submissions ranged 1-2,025 across 16 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Chin
89 reports · 3.4% death-coded
Dogo Argentino
87 reports · 3.4% death-coded
Terrier - Lakeland
90 reports · 1.1% death-coded
Borzoi
91 reports · 5.5% death-coded
Elkhound - Norwegian Grey
93 reports · 3.2% death-coded
Terrier - Fox Smooth
97 reports · 5.2% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Affenpinscher, both outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (5.7% death-coded here).

Norwegian Forest 5.7% · Cat Egyptian Mau 5.3% · Cat Crossbred Feline/cat 6.3% · Cat Scottish Fold Longhair 4.8% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (8.5 kg here).

Nigerian Dwarf 7.5 kg · Goat Primate (other) 10.1 kg · Primate Maine Coon 6.1 kg · Cat Turkish Van 5.7 kg · Cat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Affenpinscher? ▼
There are 88 adverse event reports involving Affenpinscher in the FDA database, of which 5 were death-coded (5.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Affenpinscher ranks #241 of 510 by report volume among all breeds PlainBreed indexes (#175 of 298 among dog breeds).
Where does Affenpinscher sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Affenpinscher is #241 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #175 of 298. Among breeds with at least 50 reports, its death-coded share ranks #110 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Affenpinscher? ▼
The most commonly reported adverse reactions for Affenpinscher are Vomiting (19 reports), Lethargy (see also Central nervous system depression in 'Neurological') (14 reports), Emesis (12 reports), Seizure NOS (8 reports), Diarrhoea (7 reports).
What drugs are most frequently associated with Affenpinscher adverse events? ▼
The drugs most frequently referenced in Affenpinscher adverse event reports are Milbemycin Oxime + Spinosad (21 reports), Spinosad (12 reports), Oclacitinib Maleate (4 reports), Fluralaner Chew Tablets (4 reports), Milbemycin Oxime + Praziquantel (4 reports).
What is the average age of Affenpinscher in adverse event reports? ▼
The average age of Affenpinscher at the time of adverse event reports is 6.5 years, with an average weight of 8.5 kg (18.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Affenpinscher (Dog), extract as of July 2026 extract. 88 reports · 5 death-coded (5.7% of reports, not a mortality rate) · #241 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →