Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
87
Total Reports
1
Deaths Reported
110.0%
Death Rate
6.2 yr
Avg Age at Report
Average weight at time of report: 10.0 kg (22.1 lbs)
Top Reported Reactions
Vomiting 19
Diarrhoea 9
Emesis 9
Lethargy (see also Central nervous system depression in 'Neurological') 9
Lack of efficacy - NOS 8
Anorexia 7
Bloody diarrhoea 6
Polydipsia 5
Depression 5
Polyuria 4
Seizure NOS 4
Trembling 4
Tremor 4
Other abnormal test result NOS 4
Behavioural disorder NOS 4
Most Referenced Drugs
Milbemycin Oxime + Spinosad 12
Ivermectin + Pyrantel As Pamoate Salt 10
Afoxolaner 8
Moxidectin 5
Spinosad 5
Nitenpyram 5
Oclacitinib Maleate 5
Fluralaner Chew Tablets 4
Milbemycin Oxime + Praziquantel 4
Anti-Il31 Mab Mcs Lot #1283563 3
Dexmedetomidine Hydrochloride 2
Maropitant Citrate 2
Selamectin 2
Pyrantel Pamoate;Sarolaner 2
Ivermectin, Pyrantel 1
Outcome Breakdown
Recovered/Normal
31 (39.7%)
Outcome Unknown
22 (28.2%)
Ongoing
20 (25.6%)
Recovered with Sequela
4 (5.1%)
Euthanized
1 (1.3%)
Gender Distribution
Female 50 (57.5%)
Male 34 (39.1%)
Unknown 3 (3.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 3 | |
| 2011 | 6 | |
| 2012 | 10 | |
| 2013 | 5 | |
| 2014 | 10 | |
| 2015 | 4 | |
| 2016 | 8 | |
| 2017 | 9 | |
| 2018 | 6 | |
| 2019 | 3 | |
| 2020 | 8 | |
| 2021 | 4 | |
| 2022 | 1 | |
| 2023 | 4 | |
| 2024 | 4 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #239 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.