Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
273
Total Reports
31
Deaths Reported
1140.0%
Death Rate
7.2 yr
Avg Age at Report
Average weight at time of report: 4.9 kg (10.8 lbs)
Top Reported Reactions
Vomiting 44
Lethargy (see also Central nervous system depression in 'Neurological') 33
Emesis 26
Anorexia 23
Lack of efficacy (ectoparasite) - flea 22
Lack of efficacy - NOS 20
Application site hair loss 20
Diarrhoea 18
Weight loss 18
Death by euthanasia 16
Death 15
Hypersalivation 13
Application site alopecia 13
Dehydration 12
Not eating 12
Most Referenced Drugs
Spinosad 48
Selamectin 32
Fluralaner Spot-On Solution 25
Cefovecin 24
Selamectin;Sarolaner 22
Frunevetmab 21
Imidacloprid + Moxidectin 17
Nitenpyram 13
Maropitant Citrate 9
Bexagliflozin 8
Meloxicam 7
Mirtazapine 7
Buprenorphine 7
Emodepside + Praziquantel 6
Robenacoxib 6
Outcome Breakdown
Ongoing
87 (34.0%)
Outcome Unknown
71 (27.7%)
Recovered/Normal
64 (25.0%)
Died
17 (6.6%)
Euthanized
14 (5.5%)
Recovered with Sequela
3 (1.2%)
Gender Distribution
Male 141 (51.6%)
Female 126 (46.2%)
Unknown 4 (1.5%)
Mixed 2 (0.7%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 12 | |
| 2011 | 8 | |
| 2012 | 16 | |
| 2013 | 21 | |
| 2014 | 21 | |
| 2015 | 13 | |
| 2016 | 16 | |
| 2017 | 23 | |
| 2018 | 16 | |
| 2019 | 20 | |
| 2020 | 11 | |
| 2021 | 17 | |
| 2022 | 13 | |
| 2023 | 27 | |
| 2024 | 29 | |
| 2025 | 10 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #171 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.