Total Reports
184
Above-median volume
Cat /
Breed profile · FDA CVM July 2026 extract
Sphynx adverse-event record
Adverse-event filings for Sphynx (Cat) in the FDA Center for Veterinary Medicine openFDA extract. Browse cat breeds, reactions, and outcomes below.
- #190 of 510
- by report volume (all breeds)
- 184
- FDA CVM reports on file
- 13.6%
- death-coded share of reports
- #32 of 275
- by death-coded share (≥50 reports)
How the 184 reports break down
By recorded gender -- every report on file for Sphynx, no filtering.
Annual report volume
Data updated September 2026
The verdict
According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Sphynx ranks #190 of 510 by total reports (184) and #32 of 275 by death-coded share (13.6%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).
- 93,675
- Retriever - Labrador reports (#1)
- 99.0%
- Atlantic Salmon (Salmo salar) death share (#1)
- #190
- This breed, reports of 510
- #32
- This breed, death share of 275
Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.
Release-over-release change
What changed in the latest FDA data snapshot
PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Sphynx has 184 reports now versus 180 in that prior snapshot: 4 more (2.2%).
- Report change
- +4
- Death-coded reports
- +0
- Death-coded share
- −0.3 pts
This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.
Subscribe to Sphynx changesDeaths Reported
25
of 184 reports
Death-coded share of reports
13.6%
High death-coded share
Avg Age at Report
5.0 yr
3.8 kg avg weight
Death-Coded Outcome Share
Sphynx death-coded reports 13.6%
Cross-breed median
13.6% of 184 sphynx reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 3.8 kg (8.4 lbs)
Top Reported Reactions
Vomiting 24
Death 20
Weight loss 16
Diarrhoea 13
Lethargy (see also Central nervous system depression in 'Neurological') 13
Anorexia 10
Lethargy (see also Central nervous system depression in Neurological) 9
Hypothermia 8
Most Referenced Drugs
Cefovecin 26
Buprenorphine 21
Velagliflozin Proline Monohydrate 13
Maropitant Citrate 12
Frunevetmab 11
Selamectin 8
Robenacoxib 8
Sirolimus 8
Outcome Breakdown
Ongoing
58 (31.9%)
Recovered/Normal
54 (29.7%)
Outcome Unknown
45 (24.7%)
Died
22 (12.1%)
Euthanized
3 (1.6%)
Gender Distribution
Male 104 (56.5%)
Female 72 (39.1%)
Unknown 6 (3.3%)
Mixed 2 (1.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 4 | |
| 2011 | 4 | |
| 2012 | 4 | |
| 2013 | 3 | |
| 2014 | 4 | |
| 2015 | 9 | |
| 2016 | 8 | |
| 2017 | 7 | |
| 2018 | 12 | |
| 2019 | 11 | |
| 2020 | 17 | |
| 2021 | 12 | |
| 2022 | 12 | |
| 2023 | 21 | |
| 2024 | 20 | |
| 2025 | 34 | |
| 2026 | 2 | |
Sphynx: high death-coded share in the FDA CVM extract
Signature read: Sphynx's 13.6% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Sphynx sits at #190 of 510 by report volume among all breeds and #21 of 55 among cat breeds, with 184 reports and 25 (13.6%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #32 of 275. Mean age at report: 5.0 years, average weight 3.8 kg (8.4 lbs).
Top reported signs: Vomiting (24), Death (20), Weight loss (16). Most-referenced drug: Cefovecin (26 reports), followed by Buprenorphine (21) and Velagliflozin Proline Monohydrate (13).
Outcome coding on 182 status-recorded reports is dominated by Ongoing (31.9%). Annual submissions ranged 2-2,026 across 17 years on file.
Cat Breeds With a Similar Report Volume
Showing 6 of 54 cat breeds in our dataset, ranked by closest report volume.
Nationwide breeds with similar profiles
Two openFDA-derived peer sets for Sphynx, both outside the Cat family so the neighborhoods are not species containment (the similar-volume list above stays within species).
Similar death-coded share
Nearest other-species breeds with ≥50 reports (13.6% death-coded here).
Similar average weight
Nearest other-species breeds by reported average weight (3.8 kg here).
What to do with this cat
- Compare Sphynx's report volume and death-coded share against similar-volume breeds nationwide. See similar breeds
- Read how death-coded share differs from a mortality rate before drawing conclusions. Breed-specific risks guide
- Browse every cat breed we track for comparison. All cat breeds
A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.
Frequently Asked Questions
How many FDA adverse event reports involve Sphynx? ▼
There are 184 adverse event reports involving Sphynx in the FDA database, of which 25 were death-coded (13.6% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Sphynx ranks #190 of 510 by report volume among all breeds PlainBreed indexes (#21 of 55 among cat breeds).
Where does Sphynx sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Sphynx is #190 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cat, it is #21 of 55. Among breeds with at least 50 reports, its death-coded share ranks #32 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Sphynx? ▼
The most commonly reported adverse reactions for Sphynx are Vomiting (24 reports), Death (20 reports), Weight loss (16 reports), Diarrhoea (13 reports), Lethargy (see also Central nervous system depression in 'Neurological') (13 reports).
What drugs are most frequently associated with Sphynx adverse events? ▼
The drugs most frequently referenced in Sphynx adverse event reports are Cefovecin (26 reports), Buprenorphine (21 reports), Velagliflozin Proline Monohydrate (13 reports), Maropitant Citrate (12 reports), Frunevetmab (11 reports).
What is the average age of Sphynx in adverse event reports? ▼
The average age of Sphynx at the time of adverse event reports is 5.0 years, with an average weight of 3.8 kg (8.4 lbs).
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
openFDA Animal & Veterinary Adverse Events (FDA CVM) for Sphynx (Cat), extract as of July 2026 extract. 184 reports · 25 death-coded (13.6% of reports, not a mortality rate) · #190 of 510 by volume.
Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →