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FDA CVM · 2025 release 169 reports on file

Sphynx - FDA Adverse Event Profile

Adverse-event records for Sphynx (Cat) from the FDA Center for Veterinary Medicine.

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Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 21 15.75 10.5 5.25 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Sphynx drawn from FDA CVM filings.

Data updated June 2026

The record at a glance

Sphynx's FDA record: #194 most-reported cat breed, 169 total reports, 14.8% death-coded (25 reports).

#194
most-reported cat breed
14.8%
death-coded report share
20
Death - top reaction
4.8 yr
average age at report

Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.

Total Reports

169

FDA CVM filings

Deaths Reported

25

of 169 reports

Death Rate

14.8%

death-coded share

Avg Age at Report

4.8 yr

3.8 kg avg weight

Death-Coded Outcome Share

Sphynx death-coded reports 14.8%
Cross-breed median

14.8% of 169 sphynx reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 3.8 kg (8.4 lbs)

Top Reported Reactions

Death 20
Vomiting 18
Weight loss 14
Lethargy (see also Central nervous system depression in 'Neurological') 13
Diarrhoea 12
Anorexia 9
Hypothermia 7
Lack of efficacy (ectoparasite) - flea 7

Most Referenced Drugs

Cefovecin 26
Buprenorphine 21
Maropitant Citrate 12
Frunevetmab 10
Selamectin 8
Robenacoxib 8
Velagliflozin Proline Monohydrate 8
Imidacloprid + Moxidectin 6

Outcome Breakdown

Ongoing
54 (32.3%)
Recovered/Normal
50 (29.9%)
Outcome Unknown
38 (22.8%)
Died
22 (13.2%)
Euthanized
3 (1.8%)

Gender Distribution

Male 93 (55.0%)
Female 68 (40.2%)
Unknown 6 (3.6%)
Mixed 2 (1.2%)

Reports by Year

Year Reports Trend
2010 4
2011 4
2012 4
2013 3
2014 4
2015 9
2016 8
2017 7
2018 12
2019 11
2020 17
2021 12
2022 12
2023 21
2024 20
2025 21

Sphynx Pet Health Insights

Sphynx accounts for 169 FDA adverse event reports, ranking #194 by volume among cat breeds, with 25 reports (14.8%) coded as a death outcome. Mean age at report: 4.8 years, average weight 3.8 kg (8.4 lbs).

Top reported signs: Death (20), Vomiting (18), Weight loss (14). Most-referenced drug: Cefovecin (26 reports), followed by Buprenorphine (21) and Maropitant Citrate (12).

Outcome coding on 167 status-recorded reports is dominated by Ongoing (32.3%). Annual submissions ranged 2,010-2,025 across 16 years on file.

Cat Breeds With a Similar Report Volume

Frequently Asked Questions

How many FDA adverse event reports involve Sphynx?
There are 169 adverse event reports involving Sphynx in the FDA database, with 25 reports involving death (14.8% death rate). Sphynx ranks #194 by report volume.
What are the most common adverse reactions reported for Sphynx?
The most commonly reported adverse reactions for Sphynx are Death (20 reports), Vomiting (18 reports), Weight loss (14 reports), Lethargy (see also Central nervous system depression in 'Neurological') (13 reports), Diarrhoea (12 reports).
What drugs are most frequently associated with Sphynx adverse events?
The drugs most frequently referenced in Sphynx adverse event reports are Cefovecin (26 reports), Buprenorphine (21 reports), Maropitant Citrate (12 reports), Frunevetmab (10 reports), Selamectin (8 reports).
What is the average age of Sphynx in adverse event reports?
The average age of Sphynx at the time of adverse event reports is 4.8 years, with an average weight of 3.8 kg (8.4 lbs).
Does a high number of adverse event reports mean Sphynx is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Sphynx safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.