Total Reports
280
FDA CVM filings
Cat /
FDA CVM · 2025 release 280 reports on file
Mixed (Cat) - FDA Adverse Event Profile
Adverse-event records for Mixed (Cat) (Cat) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Mixed (Cat) ranks #169 by report volume among cat breeds - 30 of 280 reports (10.7%) recorded a death outcome.
- #169
- most-reported cat breed
- 10.7%
- death-coded report share
- 74
- Lack of efficacy (ectoparasite) - flea - top reaction
- 4.9 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
30
of 280 reports
Death Rate
10.7%
death-coded share
Avg Age at Report
4.9 yr
3.6 kg avg weight
Death-Coded Outcome Share
Mixed (Cat) death-coded reports 10.7%
Cross-breed median
10.7% of 280 mixed (cat) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 3.6 kg (7.9 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 74
Vomiting 25
Application site alopecia 20
Death 18
Diarrhoea 14
Application site hair loss 14
Lack of efficacy - NOS 13
Lethargy (see also Central nervous system depression in 'Neurological') 12
Most Referenced Drugs
Selamectin 89
Nitenpyram 36
Selamectin;Sarolaner 22
Eprinomectin + Esafoxolaner + Praziquantel 22
Buprenorphine 13
Fluralaner Spot-On Solution 9
Cefovecin 8
Butorphanol Tartrate 7
Outcome Breakdown
Outcome Unknown
137 (55.5%)
Recovered/Normal
40 (16.2%)
Ongoing
33 (13.4%)
Died
23 (9.3%)
Euthanized
10 (4.0%)
Recovered with Sequela
4 (1.6%)
Gender Distribution
Mixed 161 (57.5%)
Female 55 (19.6%)
Unknown 33 (11.8%)
Male 31 (11.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 17 | |
| 2011 | 26 | |
| 2012 | 20 | |
| 2013 | 4 | |
| 2014 | 13 | |
| 2015 | 8 | |
| 2016 | 13 | |
| 2017 | 32 | |
| 2018 | 19 | |
| 2019 | 14 | |
| 2020 | 9 | |
| 2021 | 13 | |
| 2022 | 23 | |
| 2023 | 26 | |
| 2024 | 32 | |
| 2025 | 11 | |
Mixed (Cat) Pet Health Insights
Mixed (Cat) accounts for 280 FDA adverse event reports, ranking #169 by volume among cat breeds, with 30 reports (10.7%) coded as a death outcome. Mean age at report: 4.9 years, average weight 3.6 kg (7.9 lbs).
Top reported signs: Lack of efficacy (ectoparasite) - flea (74), Vomiting (25), Application site alopecia (20). Most-referenced drug: Selamectin (89 reports), followed by Nitenpyram (36) and Selamectin;Sarolaner (22).
Outcome coding on 247 status-recorded reports is dominated by Outcome Unknown (55.5%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Cat Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Mixed (Cat)? ▼
There are 280 adverse event reports involving Mixed (Cat) in the FDA database, with 30 reports involving death (10.7% death rate). Mixed (Cat) ranks #169 by report volume.
What are the most common adverse reactions reported for Mixed (Cat)? ▼
The most commonly reported adverse reactions for Mixed (Cat) are Lack of efficacy (ectoparasite) - flea (74 reports), Vomiting (25 reports), Application site alopecia (20 reports), Death (18 reports), Diarrhoea (14 reports).
What drugs are most frequently associated with Mixed (Cat) adverse events? ▼
The drugs most frequently referenced in Mixed (Cat) adverse event reports are Selamectin (89 reports), Nitenpyram (36 reports), Selamectin;Sarolaner (22 reports), Eprinomectin + Esafoxolaner + Praziquantel (22 reports), Buprenorphine (13 reports).
What is the average age of Mixed (Cat) in adverse event reports? ▼
The average age of Mixed (Cat) at the time of adverse event reports is 4.9 years, with an average weight of 3.6 kg (7.9 lbs).
Does a high number of adverse event reports mean Mixed (Cat) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Mixed (Cat) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.