Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
280
Total Reports
30
Deaths Reported
1070.0%
Death Rate
4.9 yr
Avg Age at Report
Average weight at time of report: 3.6 kg (7.9 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 74
Vomiting 25
Application site alopecia 20
Death 18
Diarrhoea 14
Application site hair loss 14
Lack of efficacy - NOS 13
Lethargy (see also Central nervous system depression in 'Neurological') 12
Death by euthanasia 11
Anorexia 11
Hypersalivation 9
Pruritus 9
Lack of efficacy (flea) 9
Application site lesion 8
Vocalisation 8
Most Referenced Drugs
Selamectin 89
Nitenpyram 36
Selamectin;Sarolaner 22
Eprinomectin + Esafoxolaner + Praziquantel 22
Buprenorphine 13
Fluralaner Spot-On Solution 9
Cefovecin 8
Butorphanol Tartrate 7
Dexmedetomidine Hydrochloride 6
Ketamine Hydrochloride 6
Anesthetic 5
Telmisartan 5
Butorphanol 5
Ketamine 5
Propofol 4
Outcome Breakdown
Outcome Unknown
137 (55.5%)
Recovered/Normal
40 (16.2%)
Ongoing
33 (13.4%)
Died
23 (9.3%)
Euthanized
10 (4.0%)
Recovered with Sequela
4 (1.6%)
Gender Distribution
Mixed 161 (57.5%)
Female 55 (19.6%)
Unknown 33 (11.8%)
Male 31 (11.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 17 | |
| 2011 | 26 | |
| 2012 | 20 | |
| 2013 | 4 | |
| 2014 | 13 | |
| 2015 | 8 | |
| 2016 | 13 | |
| 2017 | 32 | |
| 2018 | 19 | |
| 2019 | 14 | |
| 2020 | 9 | |
| 2021 | 13 | |
| 2022 | 23 | |
| 2023 | 26 | |
| 2024 | 32 | |
| 2025 | 11 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #169 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.