Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
52
Total Reports
1
Deaths Reported
190.0%
Death Rate
4.8 yr
Avg Age at Report
Average weight at time of report: 9.9 kg (21.8 lbs)
Top Reported Reactions
Vomiting 13
Emesis 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Emesis (multiple) 5
Diarrhoea 5
Lack of efficacy (ectoparasite) - flea 4
Seizure NOS 3
Vocalisation 3
Lack of efficacy - NOS 2
INEFFECTIVE, HOOKS 2
INEFFECTIVE, WHIPS 2
Inappetence 2
Pain NOS 2
Limb non-weight bearing 2
Trembling 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 21
Fluralaner 13.64% 12-Week Chew 5
Spinosad 4
Ivermectin + Pyrantel As Pamoate Salt 3
Milbemycin Oxime + Praziquantel 3
Fluralaner Chew Tablets 3
Afoxolaner 2
Trilostane 2
Grapiprant 2
Ivermectin + Pyrantel 2
Cyclosporine 2
Fenbendazole 1
Levothyroxine Sodium 1
Carprofen 1
Veterinary Diet 1
Outcome Breakdown
Recovered/Normal
27 (51.9%)
Outcome Unknown
16 (30.8%)
Ongoing
8 (15.4%)
Died
1 (1.9%)
Gender Distribution
Female 28 (53.8%)
Male 23 (44.2%)
Unknown 1 (1.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2013 | 1 | |
| 2014 | 7 | |
| 2015 | 5 | |
| 2016 | 3 | |
| 2017 | 5 | |
| 2018 | 1 | |
| 2019 | 5 | |
| 2020 | 3 | |
| 2021 | 5 | |
| 2022 | 4 | |
| 2023 | 6 | |
| 2024 | 5 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #269 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.