Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
95
Total Reports
3
Deaths Reported
320.0%
Death Rate
6.2 yr
Avg Age at Report
Average weight at time of report: 11.2 kg (24.7 lbs)
Top Reported Reactions
Vomiting 22
Lack of efficacy (ectoparasite) - flea 17
Lethargy (see also Central nervous system depression in 'Neurological') 13
Emesis 11
Emesis (multiple) 6
Diarrhoea 6
Shaking 4
Lack of efficacy (tick) 4
Lack of efficacy (bacteria) - NOS 4
Panting 3
Itching 3
Overdose 3
Deafness 3
Inappetence 3
Seizure NOS 3
Most Referenced Drugs
Milbemycin Oxime + Spinosad 25
Fluralaner 13.64% 12-Week Chew 18
Fluralaner Chew Tablets 15
Spinosad 7
Trilostane 7
Milbemycin Oxime + Praziquantel 3
Maropitant 3
Ivermectin + Pyrantel 3
Insulin Injectable Vial 3
Genta/Momet/Clotrim Ear Oint 2
Capromorelin 2
Milbemycin/Lufenuron Tablets 2
Clotrimazole + Gentamicin + Mometasone 2
Ondansetron 2
Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg 1
Outcome Breakdown
Recovered/Normal
50 (52.6%)
Ongoing
22 (23.2%)
Outcome Unknown
16 (16.8%)
Recovered with Sequela
4 (4.2%)
Euthanized
2 (2.1%)
Died
1 (1.1%)
Gender Distribution
Male 51 (53.7%)
Female 42 (44.2%)
Unknown 2 (2.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 3 | |
| 2012 | 3 | |
| 2013 | 10 | |
| 2014 | 5 | |
| 2015 | 6 | |
| 2016 | 11 | |
| 2017 | 8 | |
| 2018 | 8 | |
| 2019 | 7 | |
| 2020 | 8 | |
| 2021 | 7 | |
| 2022 | 4 | |
| 2023 | 6 | |
| 2024 | 8 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #233 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.