Drug profile

The FDA adverse-event record for Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride

3,378 FDA reports name Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#71 of 2,679
by report volume (all drugs)
3,378
adverse-event reports
0.7%
death-coded share
Unknown
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride ranks #71 of 2679 by total reports (3,378) and #1090 of 1130 by death-coded share (0.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#71
This drug, reports of 2679
#1090
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride has 3,378 reports now versus 3,296 in that prior snapshot: 82 more (2.5%).

Report change
+82
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride changes

Signature read: 3,378 reports place Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride in the upper third of FDA AER volume (#71 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,378
Total Reports
24
Deaths Reported
0.7%
Death-coded share of reports

Active Ingredients

Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride

Administration Routes

UnknownSubcutaneousIntravenous

Species Affected

Unknown 3,282
Dog 61
Cat 17
Horse 10
Rabbit 8

Most Affected Breeds

Unknown 3,282
Dog (unknown) 9
Retriever - Labrador 9
Domestic Shorthair 8
Crossbred Canine/dog 3
Paint 3
Pug 3
Siberian Husky 3
Crossbred rabbit 3
Cat (unknown) 3

Most Reported Reactions

Containers, Damaged 2,976
Containers, Leaking 2,499
Underfilling, Container 49
Vials, Leaking 43
Product defect NOS 33
Product problem 16
Seal, Abnormal 15
Containers, Abnormal 14
Pain NOS 13
Death by euthanasia 12
Contamination NOS 12
Vomiting 11

Outcome Breakdown

Recovered/Normal
38 (39.6%)
Outcome Unknown
26 (27.1%)
Died
12 (12.5%)
Euthanized
12 (12.5%)
Ongoing
7 (7.3%)
Recovered with Sequela
1 (1.0%)

Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride (#71 of 2,679 by report volume); death-coded 0.7%. PlainBreed drug row · report volume stamp 3,378 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →