Drug profile

The FDA adverse-event record for Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg

824 FDA reports name Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#210 of 2,679
by report volume (all drugs)
824
adverse-event reports
0.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg ranks #210 of 2679 by total reports (824) and #1087 of 1130 by death-coded share (0.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#210
This drug, reports of 2679
#1087
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg has 824 reports now versus 824 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg changes

Signature read: 824 reports place Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg in the upper third of FDA AER volume (#210 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
824
Total Reports
6
Deaths Reported
0.7%
Death-coded share of reports

Active Ingredients

Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg

Administration Routes

OralUnknownIntramuscular

Species Affected

Dog 649
Unknown 174
Human 1

Most Affected Breeds

Unknown 175
Crossbred Canine/dog 60
Dachshund (unspecified) 39
Dog (other) 37
Shih Tzu 36
Dog (unknown) 34
Terrier - Yorkshire 27
Chihuahua 24
Schnauzer - Miniature 24
Beagle 20

Most Reported Reactions

Digestive tract disorder NOS 327
INEFFECTIVE, HEARTWORM LARVAE 188
Lack of efficacy (endoparasite) - hookworm 161
Tablets, Abnormal 130
INEFFECTIVE, ASCARIDS NOS 130
Cardiac disorder NOS 117
Vomiting 98
No sign 62
Lethargy (see also Central nervous system depression in 'Neurological') 53
Diarrhoea 51
Lack of efficacy - NOS 45
Containers, Damaged 31

Outcome Breakdown

Outcome Unknown
417 (63.7%)
Recovered with Sequela
125 (19.1%)
Recovered/Normal
96 (14.7%)
Ongoing
11 (1.7%)
Died
6 (0.9%)

Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg (#210 of 2,679 by report volume); death-coded 0.7%. PlainBreed drug row · report volume stamp 824 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →