Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg

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824 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
824
Total Reports
6
Deaths Reported
70.0%
Death Rate

Active Ingredients

Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg

Administration Routes

OralUnknownIntramuscular

Species Affected

Dog 649
Unknown 174
Human 1

Most Affected Breeds

Unknown 175
Crossbred Canine/dog 60
Dachshund (unspecified) 39
Dog (other) 37
Shih Tzu 36
Dog (unknown) 34
Terrier - Yorkshire 27
Schnauzer - Miniature 24
Chihuahua 24
Beagle 20

Most Reported Reactions

Digestive tract disorder NOS 327
INEFFECTIVE, HEARTWORM LARVAE 188
Lack of efficacy (endoparasite) - hookworm 161
Tablets, Abnormal 130
INEFFECTIVE, ASCARIDS NOS 130
Cardiac disorder NOS 117
Vomiting 98
No sign 62
Lethargy (see also Central nervous system depression in 'Neurological') 53
Diarrhoea 51
Lack of efficacy - NOS 45
Containers, Damaged 31

Outcome Breakdown

Outcome Unknown
417 (63.7%)
Recovered with Sequela
125 (19.1%)
Recovered/Normal
96 (14.7%)
Ongoing
11 (1.7%)
Died
6 (0.9%)

Data Summary

Metric Value
Total adverse event reports 824
Reports involving death 6
Case-fatality rate (reported events) 70.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 824 adverse event reports referencing Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg, including 6 reports in which the animal died — a 70.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg. Reported administration routes include Oral, Unknown, Intramuscular. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg reports are Dog (649 reports), Unknown (174 reports), Human (1 reports), with Dog accounting for the largest share. Within those species, Unknown (175), Crossbred Canine/dog (60), Dachshund (unspecified) (39) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg are Digestive tract disorder NOS (327), INEFFECTIVE, HEARTWORM LARVAE (188), Lack of efficacy (endoparasite) - hookworm (161), Tablets, Abnormal (130). Of the 655 reports with a coded outcome, Outcome Unknown is the leading category at 63.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial