Drug profile

The FDA adverse-event record for Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg

824 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg. See the species affected, top reactions, and outcomes below.

824
adverse-event reports
0.7%
death-coded share
Dog
most-reported species
327
Digestive tract disorder NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
824
Total Reports
6
Deaths Reported
0.7%
Death Rate

Active Ingredients

Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg

Administration Routes

OralUnknownIntramuscular

Species Affected

Dog 649
Unknown 174
Human 1

Most Affected Breeds

Unknown 175
Crossbred Canine/dog 60
Dachshund (unspecified) 39
Dog (other) 37
Shih Tzu 36
Dog (unknown) 34
Terrier - Yorkshire 27
Schnauzer - Miniature 24
Chihuahua 24
Beagle 20

Most Reported Reactions

Digestive tract disorder NOS 327
INEFFECTIVE, HEARTWORM LARVAE 188
Lack of efficacy (endoparasite) - hookworm 161
Tablets, Abnormal 130
INEFFECTIVE, ASCARIDS NOS 130
Cardiac disorder NOS 117
Vomiting 98
No sign 62
Lethargy (see also Central nervous system depression in 'Neurological') 53
Diarrhoea 51
Lack of efficacy - NOS 45
Containers, Damaged 31

Outcome Breakdown

Outcome Unknown
417 (63.7%)
Recovered with Sequela
125 (19.1%)
Recovered/Normal
96 (14.7%)
Ongoing
11 (1.7%)
Died
6 (0.9%)

Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg Adverse Event Insights

824 reports name Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg; 6 recorded a death outcome (0.7% of reported events, not a population-level mortality rate). Active ingredient: Ivermectin/Pyrantel Chew. Dog 68Mcg/57Mg. Administration routes: Oral, Unknown, Intramuscular.

By species: Dog (649 reports), Unknown (174 reports), Human (1 reports). By breed: Unknown (175), Crossbred Canine/dog (60), Dachshund (unspecified) (39).

Leading clinical signs: Digestive tract disorder NOS (327), INEFFECTIVE, HEARTWORM LARVAE (188), Lack of efficacy (endoparasite) - hookworm (161), Tablets, Abnormal (130). Outcome, 655 coded reports: Outcome Unknown leads at 63.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.