Ivermectin/Pyrantel Pamoate/Praziquantel
787 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
787
Total Reports
6
Deaths Reported
80.0%
Death Rate
Active Ingredients
Ivermectin/Pyrantel Pamoate/Praziquantel
Administration Routes
OralUnknown
Species Affected
Dog 765
Unknown 22
Most Affected Breeds
Retriever - Labrador 80
Crossbred Canine/dog 49
Shih Tzu 37
Dog (unknown) 32
Maltese 32
Chihuahua 31
Terrier - Yorkshire 29
Beagle 25
Unknown 22
Shepherd Dog - German 21
Most Reported Reactions
Vomiting 376
Lack of efficacy - NOS 143
INEFFECTIVE, HEARTWORM LARVAE 96
Diarrhoea 91
Lack of efficacy (endoparasite) - hookworm 85
INEFFECTIVE, ASCARIDS NOS 73
Lethargy (see also Central nervous system depression in 'Neurological') 72
Overdose 21
Panting 16
Uncoded sign 15
Underfilling, Package 15
Lack of efficacy (endoparasite) - tapeworm 14
Outcome Breakdown
Recovered/Normal
420 (54.9%)
Outcome Unknown
291 (38.0%)
Ongoing
38 (5.0%)
Recovered with Sequela
10 (1.3%)
Died
3 (0.4%)
Euthanized
3 (0.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.