Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride

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3,430 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,430
Total Reports
86
Deaths Reported
250.0%
Death Rate

Active Ingredients

FlorfenicolMometasone FuroateTerbinafine Hydrochloride

Administration Routes

UnknownAuricular (Otic)TopicalOtherOphthalmicIntraocularOralRespiratory (Inhalation)Nasal

Species Affected

Dog 2,198
Unknown 674
Cat 471
Human 86
Rabbit 1

Most Affected Breeds

Unknown 761
Domestic Shorthair 294
Retriever - Labrador 197
Dog (unknown) 192
Retriever - Golden 133
Shih Tzu 120
Chihuahua 95
Crossbred Canine/dog 91
Maltese 82
Terrier - Yorkshire 78

Most Reported Reactions

Lack of efficacy - NOS 552
Ataxia 474
Head tilt - ear disorder 349
Vomiting 301
Nystagmus 278
Corneal ulcer 232
Behavioural disorder NOS 229
Vestibular disorder NOS 227
Lethargy (see also Central nervous system depression in 'Neurological') 216
Underfilling, Package 206
Head shake - ear disorder 200
Anorexia 196

Outcome Breakdown

Outcome Unknown
1,438 (52.1%)
Ongoing
708 (25.7%)
Recovered/Normal
513 (18.6%)
Euthanized
57 (2.1%)
Died
29 (1.1%)
Recovered with Sequela
15 (0.5%)

Data Summary

Metric Value
Total adverse event reports 3,430
Reports involving death 86
Case-fatality rate (reported events) 250.0%
Distinct species in reports 5
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 3

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 3,430 adverse event reports referencing Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride, including 86 reports in which the animal died — a 250.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredients on file: Florfenicol, Mometasone Furoate, Terbinafine Hydrochloride. Reported administration routes include Unknown, Auricular (Otic), Topical, Other. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride reports are Dog (2,198 reports), Unknown (674 reports), Cat (471 reports), with Dog accounting for the largest share. Within those species, Unknown (761), Domestic Shorthair (294), Retriever - Labrador (197) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride are Lack of efficacy - NOS (552), Ataxia (474), Head tilt - ear disorder (349), Vomiting (301). Of the 2,760 reports with a coded outcome, Outcome Unknown is the leading category at 52.1%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial