Metronidazole
3,306 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,306
Total Reports
620
Deaths Reported
1880.0%
Death Rate
Active Ingredients
Metronidazole
Administration Routes
UnknownOralIntravenousParenteralSubcutaneousTopicalOtherOphthalmic
Species Affected
Dog 2,798
Cat 353
Unknown 138
Horse 8
Human 4
Ferret 2
Chinchilla 1
Donkey 1
Other Reptiles 1
Most Affected Breeds
Retriever - Labrador 351
Domestic Shorthair 216
Unknown 153
Crossbred Canine/dog 151
Retriever - Golden 139
Shepherd Dog - German 129
Terrier - Yorkshire 128
Shih Tzu 90
Chihuahua 82
Boxer (German Boxer) 63
Most Reported Reactions
Diarrhoea 929
Vomiting 880
Lethargy (see also Central nervous system depression in 'Neurological') 570
Other abnormal test result NOS 397
Anorexia 395
Death by euthanasia 361
Elevated alanine aminotransferase (ALT) 333
Weight loss 297
Not eating 286
Bloody diarrhoea 279
Elevated serum alkaline phosphatase (SAP) 251
Death 244
Outcome Breakdown
Ongoing
1,144 (36.0%)
Recovered/Normal
774 (24.4%)
Outcome Unknown
597 (18.8%)
Euthanized
361 (11.4%)
Died
264 (8.3%)
Recovered with Sequela
35 (1.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.