Drug profile

The FDA adverse-event record for Food

441 FDA reports name Food, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#332 of 2,679
by report volume (all drugs)
441
adverse-event reports
18.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Food ranks #332 of 2679 by total reports (441) and #273 of 1130 by death-coded share (18.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#332
This drug, reports of 2679
#273
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Food has 441 reports now versus 441 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Food changes

Signature read: death-coded report count at 80 is the most distinctive stamp on Food's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
441
Total Reports
80
Deaths Reported
18.1%
Death-coded share of reports

Active Ingredients

Food

Administration Routes

OralUnknownTopical

Species Affected

Dog 360
Cat 81

Most Affected Breeds

Domestic Shorthair 51
Retriever - Labrador 45
Shih Tzu 31
Retriever - Golden 22
Terrier - Yorkshire 21
Maltese 13
Chihuahua 12
Beagle 9
Schnauzer - Miniature 9
Bichon Frise 8

Most Reported Reactions

Vomiting 109
Lethargy (see also Central nervous system depression in 'Neurological') 106
Anorexia 75
Diarrhoea 74
Other abnormal test result NOS 68
Death by euthanasia 54
Weight loss 47
Elevated serum alkaline phosphatase (SAP) 39
Lack of efficacy - NOS 36
Not eating 35
Elevated alanine aminotransferase (ALT) 31
Decreased appetite 29

Outcome Breakdown

Ongoing
272 (61.5%)
Recovered/Normal
62 (14.0%)
Euthanized
53 (12.0%)
Outcome Unknown
28 (6.3%)
Died
27 (6.1%)

Food: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Food, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Food (#332 of 2,679 by report volume); death-coded 18.1%. PlainBreed drug row · death-coded report count stamp 80 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →