Drug profile

The FDA adverse-event record for Incurin

146 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Incurin. See the species affected, top reactions, and outcomes below.

146
adverse-event reports
18.5%
death-coded share
Dog
most-reported species
27
Polydipsia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
146
Total Reports
27
Deaths Reported
18.5%
Death Rate

Active Ingredients

Incurin

Administration Routes

OralUnknownSubcutaneous

Species Affected

Dog 146

Most Affected Breeds

Retriever - Labrador 31
Crossbred Canine/dog 17
Shepherd Dog - Australian 6
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 5
Collie - Border 5
Terrier - Bull - American Pit 5
Shepherd Dog - German 5
Saint Bernard Dog 4
Doberman Pinscher 4
Shepherd (unspecified) 4

Most Reported Reactions

Polydipsia 27
Polyuria 22
Urinary incontinence 17
Lack of efficacy - NOS 17
Death by euthanasia 16
Limb weakness 16
Ataxia 15
Lethargy (see also Central nervous system depression in Neurological) 15
Vomiting 13
Panting 12
Not eating 11
Diarrhoea 11

Outcome Breakdown

Ongoing
94 (64.4%)
Euthanized
16 (11.0%)
Recovered/Normal
14 (9.6%)
Outcome Unknown
11 (7.5%)
Died
11 (7.5%)

Incurin Adverse Event Insights

146 reports name Incurin; 27 recorded a death outcome (18.5% of reported events, not a population-level mortality rate). Active ingredient: Incurin. Administration routes: Oral, Unknown, Subcutaneous.

By species: Dog (146 reports). By breed: Retriever - Labrador (31), Crossbred Canine/dog (17), Shepherd Dog - Australian (6).

Leading clinical signs: Polydipsia (27), Polyuria (22), Urinary incontinence (17), Lack of efficacy - NOS (17). Outcome, 146 coded reports: Ongoing leads at 64.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.