Drug profile

The FDA adverse-event record for Dappl Vaccine

48 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dappl Vaccine. See the species affected, top reactions, and outcomes below.

48
adverse-event reports
20.8%
death-coded share
Dog
most-reported species
20
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
48
Total Reports
10
Deaths Reported
20.8%
Death Rate

Active Ingredients

Dappl Vaccine

Administration Routes

SubcutaneousUnknown

Species Affected

Dog 48

Most Affected Breeds

Chihuahua 8
Terrier - Yorkshire 4
Crossbred Canine/dog 4
Retriever - Labrador 3
Retriever - Golden 3
Terrier - Bull - American Pit 3
Dachshund (unspecified) 2
Shepherd Dog - Australian 2
Bulldog - French 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2

Most Reported Reactions

Vomiting 20
Lethargy (see also Central nervous system depression in Neurological) 15
Diarrhoea 10
Anaphylaxis 9
Seizure NOS 9
Death by euthanasia 7
Pale mucous membrane 6
Elevated alanine aminotransferase (ALT) 5
Facial swelling (see also Skin) 4
Decreased appetite 3
Anaemia NOS 3
Lateral recumbency 3

Outcome Breakdown

Recovered/Normal
18 (37.5%)
Ongoing
17 (35.4%)
Euthanized
6 (12.5%)
Died
4 (8.3%)
Outcome Unknown
3 (6.3%)

Dappl Vaccine Adverse Event Insights

48 reports name Dappl Vaccine; 10 recorded a death outcome (20.8% of reported events, not a population-level mortality rate). Active ingredient: Dappl Vaccine. Administration routes: Subcutaneous, Unknown.

By species: Dog (48 reports). By breed: Chihuahua (8), Terrier - Yorkshire (4), Crossbred Canine/dog (4).

Leading clinical signs: Vomiting (20), Lethargy (see also Central nervous system depression in Neurological) (15), Diarrhoea (10), Anaphylaxis (9). Outcome, 48 coded reports: Recovered/Normal leads at 37.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.