Drug profile

The FDA adverse-event record for Mupirocin

121 FDA reports name Mupirocin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#704 of 2,679
by report volume (all drugs)
121
adverse-event reports
18.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Mupirocin ranks #704 of 2679 by total reports (121) and #271 of 1130 by death-coded share (18.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#704
This drug, reports of 2679
#271
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mupirocin has 121 reports now versus 117 in that prior snapshot: 4 more (3.4%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mupirocin changes

Signature read: death-coded report count at 22 is the most distinctive stamp on Mupirocin's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
121
Total Reports
22
Deaths Reported
18.2%
Death-coded share of reports

Active Ingredients

Mupirocin

Administration Routes

TopicalUnknownOralOtherAuricular (Otic)

Species Affected

Dog 87
Cat 32
Other Birds 1
Human 1

Most Affected Breeds

Domestic Shorthair 23
Retriever - Labrador 13
Shepherd Dog - German 10
Terrier - West Highland White 5
Retriever - Golden 4
Shih Tzu 4
Dog (other) 3
Cat (unknown) 3
Terrier - Bull - American Pit 3
Terrier - Bull 3

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 21
Diarrhoea 18
Vomiting 17
Anorexia 15
Other abnormal test result NOS 15
Death by euthanasia 15
Lack of efficacy - NOS 11
Pain NOS 10
Weight loss 10
Neutrophilia 10
Leucocytosis NOS 10
Elevated alanine aminotransferase (ALT) 10

Outcome Breakdown

Ongoing
52 (44.1%)
Outcome Unknown
25 (21.2%)
Recovered/Normal
17 (14.4%)
Euthanized
13 (11.0%)
Died
9 (7.6%)
Recovered with Sequela
2 (1.7%)

Mupirocin: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Mupirocin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (121 here).

Similar death-coded share

Nearest other drugs by death-coded share (18.2% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mupirocin (#704 of 2,679 by report volume); death-coded 18.2%. PlainBreed drug row · death-coded report count stamp 22 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →