Drug profile

The FDA adverse-event record for Canine Rabies Vaccine

233 FDA reports name Canine Rabies Vaccine, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#499 of 2,679
by report volume (all drugs)
233
adverse-event reports
11.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Canine Rabies Vaccine ranks #499 of 2679 by total reports (233) and #498 of 1130 by death-coded share (11.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#499
This drug, reports of 2679
#498
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Canine Rabies Vaccine has 233 reports now versus 233 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Canine Rabies Vaccine changes

Signature read: death-coded report count at 26 is the most distinctive stamp on Canine Rabies Vaccine's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
233
Total Reports
26
Deaths Reported
11.2%
Death-coded share of reports

Active Ingredients

Canine Rabies Vaccine

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 225
Cat 8

Most Affected Breeds

Retriever - Labrador 32
Chihuahua 23
Terrier - Yorkshire 11
Terrier - Bull - American Pit 11
Boxer (German Boxer) 10
Bulldog - French 8
Retriever - Golden 7
Terrier - Boston 5
Shepherd Dog - German 5
Siberian Husky 5

Most Reported Reactions

Vomiting 84
Lethargy (see also Central nervous system depression in 'Neurological') 60
Facial swelling (see also 'Skin') 49
Hives (see also 'Skin') 47
Diarrhoea 28
Anaphylaxis 26
Fever 22
Pale mucous membrane 20
Anorexia 18
Seizure NOS 18
Ataxia 13
Emesis 13

Outcome Breakdown

Ongoing
107 (45.9%)
Recovered/Normal
86 (36.9%)
Died
14 (6.0%)
Outcome Unknown
13 (5.6%)
Euthanized
12 (5.2%)
Recovered with Sequela
1 (0.4%)

Canine Rabies Vaccine: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Canine Rabies Vaccine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (233 here).

What to do with this drug

  • Compare Canine Rabies Vaccine's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Canine Rabies Vaccine (#499 of 2,679 by report volume); death-coded 11.2%. PlainBreed drug row · death-coded report count stamp 26 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →