Drug profile

The FDA adverse-event record for Doramectin; Phenol

233 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Doramectin; Phenol. See the species affected, top reactions, and outcomes below.

233
adverse-event reports
41.6%
death-coded share
Cattle
most-reported species
64
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
233
Total Reports
97
Deaths Reported
41.6%
Death Rate

Active Ingredients

Doramectin; Phenol

Administration Routes

SubcutaneousUnknownIntramuscularOralTopicalOther

Species Affected

Cattle 147
Unknown 37
Human 16
Dog 13
Sheep 8
Pig 5
Goat 2
Cat 1
Bison 1
White tailed deer 1

Most Affected Breeds

Cattle (other) 66
Unknown 56
Mixed (Cattle) 52
Aberdeen Angus 16
Sheep (unknown) 5
Holstein-Friesian also known as Holstein 5
Retriever - Labrador 3
Crossbred Bovine/Cattle 2
Crossbred Porcine/Pig 2
Goat (unknown) 2

Most Reported Reactions

Death 64
Lack of efficacy (bacteria) - NOS 44
Lack of efficacy - NOS 42
Uncoded sign 23
Other abnormal test result NOS 16
Abnormal test result 15
Abnormal necropsy finding 12
NT - Abnormal necropsy finding NOS 12
Anaphylactic-type reaction 12
INEFFECTIVE, PARASITE(S) NOS 11
CULTURE/TITER DATA ABNORMAL 11
Precipitate, Sediment 11

Outcome Breakdown

Outcome Unknown
119 (46.1%)
Died
95 (36.8%)
Recovered/Normal
23 (8.9%)
Ongoing
14 (5.4%)
Recovered with Sequela
4 (1.6%)
Euthanized
3 (1.2%)

Doramectin; Phenol Adverse Event Insights

233 reports name Doramectin; Phenol; 97 recorded a death outcome (41.6% of reported events, not a population-level mortality rate). Active ingredient: Doramectin; Phenol. Administration routes: Subcutaneous, Unknown, Intramuscular, Oral.

By species: Cattle (147 reports), Unknown (37 reports), Human (16 reports). By breed: Cattle (other) (66), Unknown (56), Mixed (Cattle) (52).

Leading clinical signs: Death (64), Lack of efficacy (bacteria) - NOS (44), Lack of efficacy - NOS (42), Uncoded sign (23). Outcome, 258 coded reports: Outcome Unknown leads at 46.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.