Drug profile

The FDA adverse-event record for Mercaptobenzothiazole

232 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Mercaptobenzothiazole. See the species affected, top reactions, and outcomes below.

232
adverse-event reports
0.9%
death-coded share
Dog
most-reported species
109
Accidental exposure - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
232
Total Reports
2
Deaths Reported
0.9%
Death Rate

Active Ingredients

Mercaptobenzothiazole

Administration Routes

TopicalOralUnknownOtherOphthalmicIntradermalRespiratory (Inhalation)

Species Affected

Dog 129
Human 80
Cat 15
Unknown 5
Other 2
Chicken 1

Most Affected Breeds

Unknown 87
Crossbred Canine/dog 24
Dog (unknown) 18
Pit Bull 14
Domestic (unspecified) 14
Shih Tzu 10
Retriever - Labrador 9
Terrier - Jack Russell 8
Chihuahua 7
Terrier - Yorkshire 5

Most Reported Reactions

Accidental exposure 109
Unclassifiable adverse event 97
No sign 61
Accidental drug intake by child 42
Vomiting 33
Depression 25
Anorexia 19
Pruritus 11
Lack of efficacy - NOS 10
Skin hyperaemia 9
Diarrhoea 9
Alopecia NOS 8

Outcome Breakdown

Outcome Unknown
5 (71.4%)
Died
2 (28.6%)

Mercaptobenzothiazole Adverse Event Insights

232 reports name Mercaptobenzothiazole; 2 recorded a death outcome (0.9% of reported events, not a population-level mortality rate). Active ingredient: Mercaptobenzothiazole. Administration routes: Topical, Oral, Unknown, Other.

By species: Dog (129 reports), Human (80 reports), Cat (15 reports). By breed: Unknown (87), Crossbred Canine/dog (24), Dog (unknown) (18).

Leading clinical signs: Accidental exposure (109), Unclassifiable adverse event (97), No sign (61), Accidental drug intake by child (42). Outcome, 7 coded reports: Outcome Unknown leads at 71.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.