Drug profile

The FDA adverse-event record for Imepitoin

193 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Imepitoin. See the species affected, top reactions, and outcomes below.

193
adverse-event reports
1.0%
death-coded share
Dog
most-reported species
28
Behavioural disorder NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
193
Total Reports
2
Deaths Reported
1.0%
Death Rate

Active Ingredients

Imepitoin

Administration Routes

OralUnknown

Species Affected

Dog 193

Most Affected Breeds

Dog (unknown) 27
Retriever - Labrador 19
Dog (other) 14
Shepherd Dog - German 9
Retriever - Golden 9
Crossbred Canine/dog 9
Dachshund (unspecified) 8
Beagle 6
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 6
Shih Tzu 6

Most Reported Reactions

Behavioural disorder NOS 28
Ataxia 23
Vomiting 22
Increased appetite 19
Aggression 17
Diarrhoea 13
Lethargy (see also Central nervous system depression in Neurological) 12
Decreased appetite 11
Drooling 11
Destructive behaviour 8
Elevated alanine aminotransferase (ALT) 8
Not eating 7

Outcome Breakdown

Recovered/Normal
120 (62.2%)
Outcome Unknown
70 (36.3%)
Euthanized
2 (1.0%)
Recovered with Sequela
1 (0.5%)

Imepitoin Adverse Event Insights

193 reports name Imepitoin; 2 recorded a death outcome (1.0% of reported events, not a population-level mortality rate). Active ingredient: Imepitoin. Administration routes: Oral, Unknown.

By species: Dog (193 reports). By breed: Dog (unknown) (27), Retriever - Labrador (19), Dog (other) (14).

Leading clinical signs: Behavioural disorder NOS (28), Ataxia (23), Vomiting (22), Increased appetite (19). Outcome, 193 coded reports: Recovered/Normal leads at 62.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.