Drug profile

The FDA adverse-event record for Nystatin + Neomycin Sulfate + Thiostrepton + Triamcinolone Acetonide

54 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Nystatin + Neomycin Sulfate + Thiostrepton + Triamcinolone Acetonide. See the species affected, top reactions, and outcomes below.

54
adverse-event reports
7.4%
death-coded share
Dog
most-reported species
9
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
54
Total Reports
4
Deaths Reported
7.4%
Death Rate

Active Ingredients

Nystatin + Neomycin Sulfate + Thiostrepton + Triamcinolone Acetonide

Administration Routes

UnknownTopicalAuricular (Otic)CutaneousOral

Species Affected

Dog 48
Cat 6

Most Affected Breeds

Retriever - Golden 10
Retriever - Labrador 8
Domestic Shorthair 4
Beagle 2
Shepherd Dog - German 2
Boxer (German Boxer) 2
Spaniel - King Charles Cavalier 2
Greyhound 2
Dog (other) 1
Crossbred Canine/dog 1

Most Reported Reactions

Vomiting 9
Emesis 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Lack of efficacy - NOS 5
Ear infection NOS 5
Not eating 3
Behavioural disorder NOS 3
Bacterial skin infection NOS 3
Polyuria 3
Decreased appetite 3
Death by euthanasia 3
Lethargy (see also Central nervous system depression in Neurological) 3

Outcome Breakdown

Outcome Unknown
17 (31.5%)
Recovered/Normal
16 (29.6%)
Ongoing
16 (29.6%)
Euthanized
3 (5.6%)
Recovered with Sequela
1 (1.9%)
Died
1 (1.9%)

Nystatin + Neomycin Sulfate + Thiostrepton + Triamcinolone Acetonide Adverse Event Insights

54 reports name Nystatin + Neomycin Sulfate + Thiostrepton + Triamcinolone Acetonide; 4 recorded a death outcome (7.4% of reported events, not a population-level mortality rate). Active ingredient: Nystatin + Neomycin Sulfate + Thiostrepton + Triamcinolone Acetonide. Administration routes: Unknown, Topical, Auricular (Otic), Cutaneous.

By species: Dog (48 reports), Cat (6 reports). By breed: Retriever - Golden (10), Retriever - Labrador (8), Domestic Shorthair (4).

Leading clinical signs: Vomiting (9), Emesis (6), Lethargy (see also Central nervous system depression in 'Neurological') (6), Lack of efficacy - NOS (5). Outcome, 54 coded reports: Outcome Unknown leads at 31.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.