Dhlpp Vaccine

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202 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
202
Total Reports
24
Deaths Reported
1190.0%
Death Rate

Active Ingredients

Dhlpp Vaccine

Administration Routes

ParenteralUnknownSubcutaneousRespiratory (Inhalation)Cutaneous

Species Affected

Dog 201
Human 1

Most Affected Breeds

Retriever - Labrador 31
Chihuahua 12
Shepherd Dog - German 11
Crossbred Canine/dog 10
Retriever - Golden 10
Pit Bull 9
Shih Tzu 6
Shepherd Dog - Australian 6
Boxer (German Boxer) 6
Maltese 6

Most Reported Reactions

Vomiting 49
Lethargy (see also Central nervous system depression in 'Neurological') 41
Emesis 32
Other abnormal test result NOS 20
Diarrhoea 19
Behavioural disorder NOS 16
Seizure NOS 15
Lack of efficacy (endoparasite) - heartworm 14
Death 12
Lack of efficacy - NOS 10
Shaking 10
Weight loss 10

Outcome Breakdown

Recovered/Normal
86 (42.6%)
Outcome Unknown
51 (25.2%)
Ongoing
33 (16.3%)
Died
18 (8.9%)
Recovered with Sequela
8 (4.0%)
Euthanized
6 (3.0%)

Data Summary

Metric Value
Total adverse event reports 202
Reports involving death 24
Case-fatality rate (reported events) 1190.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Dhlpp Vaccine Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 202 adverse event reports referencing Dhlpp Vaccine, including 24 reports in which the animal died — a 1190.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Dhlpp Vaccine. Reported administration routes include Parenteral, Unknown, Subcutaneous, Respiratory (Inhalation). These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Dhlpp Vaccine reports are Dog (201 reports), Human (1 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (31), Chihuahua (12), Shepherd Dog - German (11) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Dhlpp Vaccine are Vomiting (49), Lethargy (see also Central nervous system depression in 'Neurological') (41), Emesis (32), Other abnormal test result NOS (20). Of the 202 reports with a coded outcome, Recovered/Normal is the leading category at 42.6%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Dhlpp Vaccine.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial