Drug profile

The FDA adverse-event record for Antibacterial, Anti-Inflammatory, Antifungal

54 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Antibacterial, Anti-Inflammatory, Antifungal. Species, reactions, and outcomes follow.

#1067 of 2,679
by report volume (all drugs)
54
adverse-event reports
11.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Antibacterial, Anti-Inflammatory, Antifungal ranks #1065 of 2679 by total reports (54) and #499 of 1130 by death-coded share (11.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1065
This drug, reports of 2679
#499
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Antibacterial, Anti-Inflammatory, Antifungal has 54 reports now versus 54 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Antibacterial, Anti-Inflammatory, Antifungal changes

Signature read: report volume at 54 is the most distinctive stamp on Antibacterial, Anti-Inflammatory, Antifungal's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
54
Total Reports
6
Deaths Reported
11.1%
Death-coded share of reports

Active Ingredients

Antibacterial, Anti-Inflammatory, Antifungal

Administration Routes

Auricular (Otic)TopicalUnknown

Species Affected

Dog 52
Cat 2

Most Affected Breeds

Retriever - Labrador 9
Shih Tzu 5
Crossbred Canine/dog 4
Bulldog 3
Retriever - Golden 3
Terrier - Bull - American Pit 3
Bulldog - French 3
Terrier - Jack Russell 2
Bulldog - American 2
Spaniel (unspecified) 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 13
Other abnormal test result NOS 9
Elevated serum alkaline phosphatase (SAP) 9
Seizure NOS 8
Vomiting 8
Diarrhoea 7
Elevated alanine aminotransferase (ALT) 5
Not eating 5
Erythema (for urticaria see Immune SOC) 4
Death by euthanasia 4
Pruritus 4
Hives (see also 'Skin') 4

Outcome Breakdown

Ongoing
36 (66.7%)
Recovered/Normal
9 (16.7%)
Died
3 (5.6%)
Euthanized
3 (5.6%)
Outcome Unknown
2 (3.7%)
Recovered with Sequela
1 (1.9%)

Antibacterial, Anti-Inflammatory, Antifungal Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Antibacterial, Anti-Inflammatory, Antifungal, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (11.1% here), distinct from the volume row.

What to do with this drug

  • Compare Antibacterial, Anti-Inflammatory, Antifungal's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Antibacterial, Anti-Inflammatory, Antifungal (#1067 of 2,679 by report volume); death-coded 11.1%. PlainBreed drug row · report volume stamp 54 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →