Drug profile

The FDA adverse-event record for Orbifloxacin Oral Suspension

630 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Orbifloxacin Oral Suspension. See the species affected, top reactions, and outcomes below.

630
adverse-event reports
11.0%
death-coded share
Unknown
most-reported species
103
Containers, Damaged - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
630
Total Reports
69
Deaths Reported
11.0%
Death Rate

Active Ingredients

Orbifloxacin Oral Suspension

Administration Routes

UnknownOralOphthalmicTopicalSubcutaneous

Species Affected

Unknown 336
Cat 232
Dog 52
Human 5
Rabbit 2
Parrot 1
Guinea Pig 1
Hedgehog 1

Most Affected Breeds

Unknown 342
Domestic Shorthair 150
Domestic Longhair 19
Cat (unknown) 16
Crossbred Canine/dog 12
Domestic Mediumhair 12
Siamese 10
Chihuahua 7
Persian 5
Maltese 4

Most Reported Reactions

Containers, Damaged 103
Containers, Leaking 97
Blindness 47
Death by euthanasia 40
Appearance, Abnormal 36
Bottles, Damaged 34
Lethargy (see also Central nervous system depression in 'Neurological') 33
Underfilling, Container 32
Defect Unknown/Not Specified 31
Dilated pupils 30
Emesis (multiple) 29
Death 27

Outcome Breakdown

Ongoing
84 (28.6%)
Recovered/Normal
73 (24.8%)
Euthanized
40 (13.6%)
Outcome Unknown
38 (12.9%)
Recovered with Sequela
30 (10.2%)
Died
29 (9.9%)

Orbifloxacin Oral Suspension Adverse Event Insights

630 reports name Orbifloxacin Oral Suspension; 69 recorded a death outcome (11.0% of reported events, not a population-level mortality rate). Active ingredient: Orbifloxacin Oral Suspension. Administration routes: Unknown, Oral, Ophthalmic, Topical.

By species: Unknown (336 reports), Cat (232 reports), Dog (52 reports). By breed: Unknown (342), Domestic Shorthair (150), Domestic Longhair (19).

Leading clinical signs: Containers, Damaged (103), Containers, Leaking (97), Blindness (47), Death by euthanasia (40). Outcome, 294 coded reports: Ongoing leads at 28.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.