Total Reports
704
FDA CVM filings
Dog /
FDA CVM · 2025 release 704 reports on file
Spaniel - Boykin - FDA Adverse Event Profile
Adverse-event records for Spaniel - Boykin (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Spaniel - Boykin is #121 by FDA report volume; 1.6% of its 704 reports (11) were death-coded.
- #121
- most-reported dog breed
- 1.6%
- death-coded report share
- 140
- Lack of efficacy (endoparasite) - heartworm - top reaction
- 4.3 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
11
of 704 reports
Death Rate
1.6%
death-coded share
Avg Age at Report
4.3 yr
16.7 kg avg weight
Death-Coded Outcome Share
Spaniel - Boykin death-coded reports 1.6%
Cross-breed median
1.6% of 704 spaniel - boykin reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 16.7 kg (36.8 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 140
Vomiting 126
Lack of efficacy (endoparasite) - hookworm 66
INEFFECTIVE, HEARTWORM LARVAE 54
Emesis 42
Lethargy (see also Central nervous system depression in 'Neurological') 39
Lack of efficacy - NOS 35
Diarrhoea 30
Most Referenced Drugs
Milbemycin Oxime + Spinosad 143
Ivermectin + Pyrantel As Pamoate Salt 122
Moxidectin 85
Pyrantel Pamoate;Sarolaner 58
Milbemycin Oxime + Praziquantel 53
Afoxolaner 43
Spinosad 30
Oclacitinib Maleate 21
Outcome Breakdown
Outcome Unknown
227 (34.2%)
Ongoing
218 (32.8%)
Recovered/Normal
174 (26.2%)
Recovered with Sequela
34 (5.1%)
Euthanized
7 (1.1%)
Died
4 (0.6%)
Gender Distribution
Male 363 (51.6%)
Female 333 (47.3%)
Unknown 7 (1.0%)
Mixed 1 (0.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 21 | |
| 2011 | 31 | |
| 2012 | 33 | |
| 2013 | 32 | |
| 2014 | 28 | |
| 2015 | 35 | |
| 2016 | 41 | |
| 2017 | 42 | |
| 2018 | 42 | |
| 2019 | 47 | |
| 2020 | 48 | |
| 2021 | 48 | |
| 2022 | 63 | |
| 2023 | 68 | |
| 2024 | 65 | |
| 2025 | 60 | |
Spaniel - Boykin Pet Health Insights
Spaniel - Boykin accounts for 704 FDA adverse event reports, ranking #121 by volume among dog breeds, with 11 reports (1.6%) coded as a death outcome. Mean age at report: 4.3 years, average weight 16.7 kg (36.8 lbs).
Top reported signs: Lack of efficacy (endoparasite) - heartworm (140), Vomiting (126), Lack of efficacy (endoparasite) - hookworm (66). Most-referenced drug: Milbemycin Oxime + Spinosad (143 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (122) and Moxidectin (85).
Outcome coding on 664 status-recorded reports is dominated by Outcome Unknown (34.2%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Spaniel - Boykin? ▼
There are 704 adverse event reports involving Spaniel - Boykin in the FDA database, with 11 reports involving death (1.6% death rate). Spaniel - Boykin ranks #121 by report volume.
What are the most common adverse reactions reported for Spaniel - Boykin? ▼
The most commonly reported adverse reactions for Spaniel - Boykin are Lack of efficacy (endoparasite) - heartworm (140 reports), Vomiting (126 reports), Lack of efficacy (endoparasite) - hookworm (66 reports), INEFFECTIVE, HEARTWORM LARVAE (54 reports), Emesis (42 reports).
What drugs are most frequently associated with Spaniel - Boykin adverse events? ▼
The drugs most frequently referenced in Spaniel - Boykin adverse event reports are Milbemycin Oxime + Spinosad (143 reports), Ivermectin + Pyrantel As Pamoate Salt (122 reports), Moxidectin (85 reports), Pyrantel Pamoate;Sarolaner (58 reports), Milbemycin Oxime + Praziquantel (53 reports).
What is the average age of Spaniel - Boykin in adverse event reports? ▼
The average age of Spaniel - Boykin at the time of adverse event reports is 4.3 years, with an average weight of 16.7 kg (36.8 lbs).
Does a high number of adverse event reports mean Spaniel - Boykin is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Spaniel - Boykin safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.