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Breed profile · FDA CVM July 2026 extract

Shepherd Dog - Dutch adverse-event record

Adverse-event filings for Shepherd Dog - Dutch (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#172 of 510
by report volume (all breeds)
267
FDA CVM reports on file
1.1%
death-coded share of reports
#273 of 275
by death-coded share (≥50 reports)

How the 267 reports break down

By recorded gender -- every report on file for Shepherd Dog - Dutch, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 34 25.5 17 8.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Shepherd Dog - Dutch drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Shepherd Dog - Dutch ranks #172 of 510 by total reports (267) and #273 of 275 by death-coded share (1.1%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#172
This breed, reports of 510
#273
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Shepherd Dog - Dutch has 267 reports now versus 267 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Shepherd Dog - Dutch changes

Total Reports

267

Above-median volume

Deaths Reported

3

of 267 reports

Death-coded share of reports

1.1%

Lowest death-coded share

Avg Age at Report

4.3 yr

29.7 kg avg weight

Breed Safety Scorecard

C (59/100)

A weighted composite across 3 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate A+
1.1%

Share of reports coded as a fatality

Euthanasia rate N/A
N/A

Share of reports resulting in euthanasia

Full recovery rate F
25.1%

Share of reports coded "Recovered/Normal"

5-year trend F
+33%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Shepherd Dog - Dutch death-coded reports 1.1%
Cross-breed median

1.1% of 267 shepherd dog - dutch reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Shepherd Dog - Dutch's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

1% 1st percentile Higher share than 1% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Shepherd Dog - Dutch 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 29.7 kg (65.5 lbs)

Top Reported Reactions

Lack of efficacy (endoparasite) - heartworm 52
Vomiting 51
INEFFECTIVE, HEARTWORM LARVAE 23
Lethargy (see also Central nervous system depression in 'Neurological') 16
Diarrhoea 15
Emesis 10
Lack of efficacy (endoparasite) - hookworm 10
Lack of efficacy (ectoparasite) - tick NOS 10

Most Referenced Drugs

Milbemycin Oxime + Spinosad 41
Ivermectin + Pyrantel As Pamoate Salt 40
Moxidectin 30
Pyrantel Pamoate;Sarolaner 26
Afoxolaner 15
Milbemycin Oxime + Praziquantel 15
Bedinvetmab 12
Sarolaner 11

Outcome Breakdown

Ongoing
89 (34.6%)
Outcome Unknown
84 (32.7%)
Recovered/Normal
67 (26.1%)
Recovered with Sequela
14 (5.4%)
Died
3 (1.2%)

Gender Distribution

Male 154 (57.7%)
Female 110 (41.2%)
Unknown 2 (0.7%)
Mixed 1 (0.4%)

Reports by Year

Year Reports Trend
2010 4
2011 6
2012 8
2013 10
2014 8
2015 13
2016 17
2017 19
2018 12
2019 18
2020 31
2021 18
2022 15
2023 30
2024 34
2025 24

Shepherd Dog - Dutch: low death-coded share in the FDA CVM extract

Signature read: Shepherd Dog - Dutch's 1.1% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Shepherd Dog - Dutch sits at #172 of 510 by report volume among all breeds and #138 of 298 among dog breeds, with 267 reports and 3 (1.1%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #273 of 275. Mean age at report: 4.3 years, average weight 29.7 kg (65.5 lbs).

Top reported signs: Lack of efficacy (endoparasite) - heartworm (52), Vomiting (51), INEFFECTIVE, HEARTWORM LARVAE (23). Most-referenced drug: Milbemycin Oxime + Spinosad (41 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (40) and Moxidectin (30).

Outcome coding on 257 status-recorded reports is dominated by Ongoing (34.6%). Annual submissions ranged 4-2,025 across 16 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Retriever - Nova Scotia Duck Tolling
250 reports · 1.6% death-coded
Irish Wolfhound
290 reports · 6.9% death-coded
Cattle Dog - Flanders (Bouvier)
292 reports · 7.2% death-coded
Terrier - Norwich
234 reports · 3.0% death-coded
Setter - Gordon
231 reports · 5.2% death-coded
Griffon - French Wire-haired Pointing
227 reports · 0.4% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Shepherd Dog - Dutch, both outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (1.1% death-coded here).

Turkish Angora 1.3% · Cat Hanovarian 2.2% · Horse Warmblood - Dutch 2.7% · Horse Oldenburg 2.8% · Horse

Similar average weight

Nearest other-species breeds by reported average weight (29.7 kg here).

Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep Nubian 32.8 kg · Goat Mixed (Sheep) 24.9 kg · Sheep

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Shepherd Dog - Dutch? ▼
There are 267 adverse event reports involving Shepherd Dog - Dutch in the FDA database, of which 3 were death-coded (1.1% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Shepherd Dog - Dutch ranks #172 of 510 by report volume among all breeds PlainBreed indexes (#138 of 298 among dog breeds).
Where does Shepherd Dog - Dutch sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Shepherd Dog - Dutch is #172 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #138 of 298. Among breeds with at least 50 reports, its death-coded share ranks #273 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Shepherd Dog - Dutch? ▼
The most commonly reported adverse reactions for Shepherd Dog - Dutch are Lack of efficacy (endoparasite) - heartworm (52 reports), Vomiting (51 reports), INEFFECTIVE, HEARTWORM LARVAE (23 reports), Lethargy (see also Central nervous system depression in 'Neurological') (16 reports), Diarrhoea (15 reports).
What drugs are most frequently associated with Shepherd Dog - Dutch adverse events? ▼
The drugs most frequently referenced in Shepherd Dog - Dutch adverse event reports are Milbemycin Oxime + Spinosad (41 reports), Ivermectin + Pyrantel As Pamoate Salt (40 reports), Moxidectin (30 reports), Pyrantel Pamoate;Sarolaner (26 reports), Afoxolaner (15 reports).
What is the average age of Shepherd Dog - Dutch in adverse event reports? ▼
The average age of Shepherd Dog - Dutch at the time of adverse event reports is 4.3 years, with an average weight of 29.7 kg (65.5 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Shepherd Dog - Dutch (Dog), extract as of July 2026 extract. 267 reports · 3 death-coded (1.1% of reports, not a mortality rate) · #172 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →