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Breed profile · FDA CVM July 2026 extract

Plott adverse-event record

Adverse-event filings for Plott (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#165 of 510
by report volume (all breeds)
325
FDA CVM reports on file
3.1%
death-coded share of reports
#232 of 275
by death-coded share (≥50 reports)

How the 325 reports break down

By recorded gender -- every report on file for Plott, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 42 31.5 21 10.5 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Plott drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Plott ranks #165 of 510 by total reports (325) and #228 of 275 by death-coded share (3.1%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#165
This breed, reports of 510
#228
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Plott has 325 reports now versus 317 in that prior snapshot: 8 more (2.5%).

Report change
+8
Death-coded reports
+1
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Plott changes

Total Reports

325

Above-median volume

Deaths Reported

10

of 325 reports

Death-coded share of reports

3.1%

Lowest death-coded share

Avg Age at Report

4.2 yr

26.9 kg avg weight

Breed Safety Scorecard

C+ (60/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate A
3.1%

Share of reports coded as a fatality

Euthanasia rate D
2.2%

Share of reports resulting in euthanasia

Full recovery rate F
20.9%

Share of reports coded "Recovered/Normal"

5-year trend B-
-9%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Plott death-coded reports 3.1%
Cross-breed median

3.1% of 325 plott reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Plott's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

3% 16th percentile Higher share than 16% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Plott 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 26.9 kg (59.3 lbs)

Top Reported Reactions

Lack of efficacy (endoparasite) - heartworm 63
Vomiting 51
Lack of efficacy (endoparasite) - hookworm 30
Diarrhoea 26
Emesis 20
Lethargy (see also Central nervous system depression in 'Neurological') 19
Digestive tract disorder NOS 17
INEFFECTIVE, HOOKS 14

Most Referenced Drugs

Milbemycin Oxime + Spinosad 61
Pyrantel Pamoate;Sarolaner 59
Milbemycin Oxime + Praziquantel 48
Ivermectin + Pyrantel As Pamoate Salt 36
Moxidectin 26
Sarolaner 14
Bedinvetmab 13
Afoxolaner 12

Outcome Breakdown

Ongoing
121 (37.2%)
Outcome Unknown
112 (34.5%)
Recovered/Normal
68 (20.9%)
Recovered with Sequela
14 (4.3%)
Euthanized
7 (2.2%)
Died
3 (0.9%)

Gender Distribution

Female 168 (51.7%)
Male 154 (47.4%)
Unknown 3 (0.9%)

Reports by Year

Year Reports Trend
2011 3
2012 9
2013 11
2014 16
2015 12
2016 12
2017 14
2018 33
2019 27
2020 33
2021 23
2022 38
2023 26
2024 42
2025 21
2026 5

Plott: low death-coded share in the FDA CVM extract

Signature read: Plott's 3.1% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Plott sits at #165 of 510 by report volume among all breeds and #134 of 298 among dog breeds, with 325 reports and 10 (3.1%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #232 of 275. Mean age at report: 4.2 years, average weight 26.9 kg (59.3 lbs).

Top reported signs: Lack of efficacy (endoparasite) - heartworm (63), Vomiting (51), Lack of efficacy (endoparasite) - hookworm (30). Most-referenced drug: Milbemycin Oxime + Spinosad (61 reports), followed by Pyrantel Pamoate;Sarolaner (59) and Milbemycin Oxime + Praziquantel (48).

Outcome coding on 325 status-recorded reports is dominated by Ongoing (37.2%). Annual submissions ranged 3-2,026 across 16 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Terrier - Border
332 reports · 3.0% death-coded
Spitz - Dutch (Keeshond)
335 reports · 6.9% death-coded
Schipperke
336 reports · 4.8% death-coded
Foxhound - American
308 reports · 3.2% death-coded
Coonhound - Bluetick
343 reports · 3.2% death-coded
Terrier - Welsh
347 reports · 4.0% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Plott drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (3.1% death-coded here).

Birman (Sacred Birman) 3.1% · Cat Oriental 3.1% · Cat Oldenburg 2.8% · Horse Warmblood - Dutch 2.7% · Horse

Similar average weight

Nearest other-species breeds by reported average weight (26.9 kg here).

Mixed (Sheep) 24.9 kg · Sheep Crossbred Caprine/goat 21.7 kg · Goat Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Plott? ▼
There are 325 adverse event reports involving Plott in the FDA database, of which 10 were death-coded (3.1% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Plott ranks #165 of 510 by report volume among all breeds PlainBreed indexes (#134 of 298 among dog breeds).
Where does Plott sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Plott is #165 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #134 of 298. Among breeds with at least 50 reports, its death-coded share ranks #232 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Plott? ▼
The most commonly reported adverse reactions for Plott are Lack of efficacy (endoparasite) - heartworm (63 reports), Vomiting (51 reports), Lack of efficacy (endoparasite) - hookworm (30 reports), Diarrhoea (26 reports), Emesis (20 reports).
What drugs are most frequently associated with Plott adverse events? ▼
The drugs most frequently referenced in Plott adverse event reports are Milbemycin Oxime + Spinosad (61 reports), Pyrantel Pamoate;Sarolaner (59 reports), Milbemycin Oxime + Praziquantel (48 reports), Ivermectin + Pyrantel As Pamoate Salt (36 reports), Moxidectin (26 reports).
What is the average age of Plott in adverse event reports? ▼
The average age of Plott at the time of adverse event reports is 4.2 years, with an average weight of 26.9 kg (59.3 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Plott (Dog), extract as of July 2026 extract. 325 reports · 10 death-coded (3.1% of reports, not a mortality rate) · #165 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →