Total Reports
310
FDA CVM filings
Dog /
FDA CVM · 2025 release 310 reports on file
Plott - FDA Adverse Event Profile
Adverse-event records for Plott (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Plott is #165 by FDA report volume; 2.9% of its 310 reports (9) were death-coded.
- #165
- most-reported dog breed
- 2.9%
- death-coded report share
- 59
- Lack of efficacy (endoparasite) - heartworm - top reaction
- 4.1 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
9
of 310 reports
Death Rate
2.9%
death-coded share
Avg Age at Report
4.1 yr
26.9 kg avg weight
Death-Coded Outcome Share
Plott death-coded reports 2.9%
Cross-breed median
2.9% of 310 plott reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 26.9 kg (59.3 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 59
Vomiting 48
Lack of efficacy (endoparasite) - hookworm 30
Diarrhoea 22
Emesis 20
Lethargy (see also Central nervous system depression in 'Neurological') 19
Digestive tract disorder NOS 17
INEFFECTIVE, HOOKS 14
Most Referenced Drugs
Milbemycin Oxime + Spinosad 61
Pyrantel Pamoate;Sarolaner 56
Milbemycin Oxime + Praziquantel 46
Ivermectin + Pyrantel As Pamoate Salt 36
Moxidectin 25
Sarolaner 14
Afoxolaner 12
Gabapentin 11
Outcome Breakdown
Ongoing
114 (36.8%)
Outcome Unknown
109 (35.2%)
Recovered/Normal
64 (20.6%)
Recovered with Sequela
14 (4.5%)
Euthanized
6 (1.9%)
Died
3 (1.0%)
Gender Distribution
Female 160 (51.6%)
Male 148 (47.7%)
Unknown 2 (0.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 3 | |
| 2012 | 9 | |
| 2013 | 11 | |
| 2014 | 16 | |
| 2015 | 12 | |
| 2016 | 12 | |
| 2017 | 14 | |
| 2018 | 33 | |
| 2019 | 27 | |
| 2020 | 33 | |
| 2021 | 23 | |
| 2022 | 37 | |
| 2023 | 25 | |
| 2024 | 42 | |
| 2025 | 13 | |
Plott Pet Health Insights
Plott accounts for 310 FDA adverse event reports, ranking #165 by volume among dog breeds, with 9 reports (2.9%) coded as a death outcome. Mean age at report: 4.1 years, average weight 26.9 kg (59.3 lbs).
Top reported signs: Lack of efficacy (endoparasite) - heartworm (59), Vomiting (48), Lack of efficacy (endoparasite) - hookworm (30). Most-referenced drug: Milbemycin Oxime + Spinosad (61 reports), followed by Pyrantel Pamoate;Sarolaner (56) and Milbemycin Oxime + Praziquantel (46).
Outcome coding on 310 status-recorded reports is dominated by Ongoing (36.8%). Annual submissions ranged 2,011-2,025 across 15 years on file.
Dog Breeds With a Similar Report Volume
Terrier - Border
317 reports · 3.2% death rate
Foxhound - American
291 reports · 3.4% death rate
Coonhound - Bluetick
330 reports · 3.3% death rate
Spitz - Dutch (Keeshond)
331 reports · 6.9% death rate
Cattle Dog - Flanders (Bouvier)
287 reports · 7.0% death rate
Schipperke
333 reports · 4.8% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Plott? ▼
There are 310 adverse event reports involving Plott in the FDA database, with 9 reports involving death (2.9% death rate). Plott ranks #165 by report volume.
What are the most common adverse reactions reported for Plott? ▼
The most commonly reported adverse reactions for Plott are Lack of efficacy (endoparasite) - heartworm (59 reports), Vomiting (48 reports), Lack of efficacy (endoparasite) - hookworm (30 reports), Diarrhoea (22 reports), Emesis (20 reports).
What drugs are most frequently associated with Plott adverse events? ▼
The drugs most frequently referenced in Plott adverse event reports are Milbemycin Oxime + Spinosad (61 reports), Pyrantel Pamoate;Sarolaner (56 reports), Milbemycin Oxime + Praziquantel (46 reports), Ivermectin + Pyrantel As Pamoate Salt (36 reports), Moxidectin (25 reports).
What is the average age of Plott in adverse event reports? ▼
The average age of Plott at the time of adverse event reports is 4.1 years, with an average weight of 26.9 kg (59.3 lbs).
Does a high number of adverse event reports mean Plott is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Plott safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.