Total Reports
333
FDA CVM filings
Dog /
FDA CVM · 2025 release 333 reports on file
Schipperke - FDA Adverse Event Profile
Adverse-event records for Schipperke (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Schipperke ranks #160 by report volume among dog breeds - 16 of 333 reports (4.8%) recorded a death outcome.
- #160
- most-reported dog breed
- 4.8%
- death-coded report share
- 62
- Vomiting - top reaction
- 7.9 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
16
of 333 reports
Death Rate
4.8%
death-coded share
Avg Age at Report
7.9 yr
8.5 kg avg weight
Death-Coded Outcome Share
Schipperke death-coded reports 4.8%
Cross-breed median
4.8% of 333 schipperke reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 8.5 kg (18.7 lbs)
Top Reported Reactions
Vomiting 62
Lethargy (see also Central nervous system depression in 'Neurological') 38
Diarrhoea 37
Emesis 26
Lack of efficacy - NOS 24
Seizure NOS 21
Lack of efficacy (ectoparasite) - flea 20
Digestive tract disorder NOS 18
Most Referenced Drugs
Milbemycin Oxime + Spinosad 59
Spinosad 38
Ivermectin + Pyrantel As Pamoate Salt 32
Afoxolaner 27
Trilostane 14
Selamectin 12
Milbemycin Oxime + Praziquantel 12
Fluralaner Chew Tablets 9
Outcome Breakdown
Recovered/Normal
113 (37.8%)
Outcome Unknown
103 (34.4%)
Ongoing
50 (16.7%)
Recovered with Sequela
17 (5.7%)
Euthanized
10 (3.3%)
Died
6 (2.0%)
Gender Distribution
Female 179 (53.8%)
Male 144 (43.2%)
Unknown 8 (2.4%)
Mixed 2 (0.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 17 | |
| 2011 | 31 | |
| 2012 | 27 | |
| 2013 | 34 | |
| 2014 | 38 | |
| 2015 | 28 | |
| 2016 | 33 | |
| 2017 | 29 | |
| 2018 | 16 | |
| 2019 | 13 | |
| 2020 | 14 | |
| 2021 | 16 | |
| 2022 | 9 | |
| 2023 | 9 | |
| 2024 | 10 | |
| 2025 | 9 | |
Schipperke Pet Health Insights
Schipperke accounts for 333 FDA adverse event reports, ranking #160 by volume among dog breeds, with 16 reports (4.8%) coded as a death outcome. Mean age at report: 7.9 years, average weight 8.5 kg (18.7 lbs).
Top reported signs: Vomiting (62), Lethargy (see also Central nervous system depression in 'Neurological') (38), Diarrhoea (37). Most-referenced drug: Milbemycin Oxime + Spinosad (59 reports), followed by Spinosad (38) and Ivermectin + Pyrantel As Pamoate Salt (32).
Outcome coding on 299 status-recorded reports is dominated by Recovered/Normal (37.8%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Schipperke? ▼
There are 333 adverse event reports involving Schipperke in the FDA database, with 16 reports involving death (4.8% death rate). Schipperke ranks #160 by report volume.
What are the most common adverse reactions reported for Schipperke? ▼
The most commonly reported adverse reactions for Schipperke are Vomiting (62 reports), Lethargy (see also Central nervous system depression in 'Neurological') (38 reports), Diarrhoea (37 reports), Emesis (26 reports), Lack of efficacy - NOS (24 reports).
What drugs are most frequently associated with Schipperke adverse events? ▼
The drugs most frequently referenced in Schipperke adverse event reports are Milbemycin Oxime + Spinosad (59 reports), Spinosad (38 reports), Ivermectin + Pyrantel As Pamoate Salt (32 reports), Afoxolaner (27 reports), Trilostane (14 reports).
What is the average age of Schipperke in adverse event reports? ▼
The average age of Schipperke at the time of adverse event reports is 7.9 years, with an average weight of 8.5 kg (18.7 lbs).
Does a high number of adverse event reports mean Schipperke is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Schipperke safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.