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Breed profile · FDA CVM July 2026 extract

Schipperke adverse-event record

Adverse-event filings for Schipperke (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#161 of 510
by report volume (all breeds)
336
FDA CVM reports on file
4.8%
death-coded share of reports
#141 of 275
by death-coded share (≥50 reports)

How the 336 reports break down

By recorded gender -- every report on file for Schipperke, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 16 12 8 4 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Schipperke drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Schipperke ranks #161 of 510 by total reports (336) and #141 of 275 by death-coded share (4.8%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#161
This breed, reports of 510
#141
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Schipperke has 336 reports now versus 334 in that prior snapshot: 2 more (0.6%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Schipperke changes

Total Reports

336

Above-median volume

Deaths Reported

16

of 336 reports

Death-coded share of reports

4.8%

Below-median death-coded share

Avg Age at Report

7.9 yr

8.5 kg avg weight

Breed Safety Scorecard

C (56/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate D
4.8%

Share of reports coded as a fatality

Euthanasia rate F
3.0%

Share of reports resulting in euthanasia

Full recovery rate B
34.2%

Share of reports coded "Recovered/Normal"

5-year trend A-
-25%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Schipperke death-coded reports 4.8%
Cross-breed median

4.8% of 336 schipperke reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Schipperke's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

5% 49th percentile Higher share than 49% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Schipperke 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 8.5 kg (18.7 lbs)

Top Reported Reactions

Vomiting 63
Lethargy (see also Central nervous system depression in 'Neurological') 38
Diarrhoea 37
Emesis 26
Lack of efficacy - NOS 24
Lack of efficacy (ectoparasite) - flea 21
Seizure NOS 21
Lack of efficacy (endoparasite) - hookworm 18

Most Referenced Drugs

Milbemycin Oxime + Spinosad 59
Spinosad 38
Ivermectin + Pyrantel As Pamoate Salt 32
Afoxolaner 27
Trilostane 14
Selamectin 12
Milbemycin Oxime + Praziquantel 12
Fluralaner Chew Tablets 9

Outcome Breakdown

Recovered/Normal
115 (38.1%)
Outcome Unknown
103 (34.1%)
Ongoing
51 (16.9%)
Recovered with Sequela
17 (5.6%)
Euthanized
10 (3.3%)
Died
6 (2.0%)

Gender Distribution

Female 181 (53.9%)
Male 145 (43.2%)
Unknown 8 (2.4%)
Mixed 2 (0.6%)

Reports by Year

Year Reports Trend
2010 17
2011 31
2012 27
2013 34
2014 38
2015 28
2016 33
2017 29
2018 16
2019 13
2020 14
2021 16
2022 9
2023 9
2024 10
2025 12

Schipperke: high-volume FDA adverse-event cohort

Signature read: 336 reports place Schipperke in the upper third of breed filing volume (#161 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Schipperke sits at #161 of 510 by report volume among all breeds and #131 of 298 among dog breeds, with 336 reports and 16 (4.8%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #141 of 275. Mean age at report: 7.9 years, average weight 8.5 kg (18.7 lbs).

Top reported signs: Vomiting (63), Lethargy (see also Central nervous system depression in 'Neurological') (38), Diarrhoea (37). Most-referenced drug: Milbemycin Oxime + Spinosad (59 reports), followed by Spinosad (38) and Ivermectin + Pyrantel As Pamoate Salt (32).

Outcome coding on 302 status-recorded reports is dominated by Recovered/Normal (38.1%). Annual submissions ranged 9-2,025 across 16 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Spitz - Dutch (Keeshond)
335 reports · 6.9% death-coded
Terrier - Border
332 reports · 3.0% death-coded
Coonhound - Bluetick
343 reports · 3.2% death-coded
Plott
325 reports · 3.1% death-coded
Terrier - Welsh
347 reports · 4.0% death-coded
Schnauzer - Giant
357 reports · 6.2% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Schipperke drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (4.8% death-coded here).

Scottish Fold Longhair 4.8% · Cat Bengal 4.6% · Cat Egyptian Mau 5.3% · Cat Siberian 4.2% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (8.5 kg here).

Nigerian Dwarf 7.5 kg · Goat Primate (other) 10.1 kg · Primate Maine Coon 6.1 kg · Cat Norwegian Forest 5.8 kg · Cat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Schipperke? ▼
There are 336 adverse event reports involving Schipperke in the FDA database, of which 16 were death-coded (4.8% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Schipperke ranks #161 of 510 by report volume among all breeds PlainBreed indexes (#131 of 298 among dog breeds).
Where does Schipperke sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Schipperke is #161 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #131 of 298. Among breeds with at least 50 reports, its death-coded share ranks #141 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Schipperke? ▼
The most commonly reported adverse reactions for Schipperke are Vomiting (63 reports), Lethargy (see also Central nervous system depression in 'Neurological') (38 reports), Diarrhoea (37 reports), Emesis (26 reports), Lack of efficacy - NOS (24 reports).
What drugs are most frequently associated with Schipperke adverse events? ▼
The drugs most frequently referenced in Schipperke adverse event reports are Milbemycin Oxime + Spinosad (59 reports), Spinosad (38 reports), Ivermectin + Pyrantel As Pamoate Salt (32 reports), Afoxolaner (27 reports), Trilostane (14 reports).
What is the average age of Schipperke in adverse event reports? ▼
The average age of Schipperke at the time of adverse event reports is 7.9 years, with an average weight of 8.5 kg (18.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Schipperke (Dog), extract as of July 2026 extract. 336 reports · 16 death-coded (4.8% of reports, not a mortality rate) · #161 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →