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Breed profile · FDA CVM July 2026 extract

Hereford cattle adverse-event record

Adverse-event filings for Hereford cattle (Cattle) in the FDA Center for Veterinary Medicine openFDA extract. Browse cattle breeds, reactions, and outcomes below.

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#210 of 510
by report volume (all breeds)
148
FDA CVM reports on file
31.8%
death-coded share of reports
#24 of 275
by death-coded share (≥50 reports)

How the 148 reports break down

By recorded gender -- every report on file for Hereford cattle, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 10 7.5 5 2.5 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Hereford cattle drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Hereford cattle ranks #210 of 510 by total reports (148) and #24 of 275 by death-coded share (31.8%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#210
This breed, reports of 510
#24
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hereford cattle has 148 reports now versus 147 in that prior snapshot: 1 more (0.7%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hereford cattle changes

Total Reports

148

Above-median volume

Deaths Reported

47

of 148 reports

Death-coded share of reports

31.8%

Highest death-coded share

Avg Age at Report

1.2 yr

271.8 kg avg weight

Death-Coded Outcome Share

Hereford cattle death-coded reports 31.8%
Cross-breed median

31.8% of 148 hereford cattle reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Hereford cattle's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

32% 91st percentile Higher share than 91% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). Below this entry. 20%–25%: 2 indexed breeds (1%). Below this entry. 25%–30%: 3 indexed breeds (1%). Below this entry. 30%–35%: 4 indexed breeds (1%). This entry sits in this band. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Hereford cattle 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 271.8 kg (599.3 lbs)

Top Reported Reactions

Death 40
Lack of efficacy - NOS 24
Lack of efficacy (ectoparasite) - lice 17
Injection site swelling 14
INEFFECTIVE, ESTRUS SYNCHRONIZ 10
Dyspnoea 6
Anaphylaxis 6
Hypersalivation 5

Most Referenced Drugs

Dinoprost Tromethamine 13
Progesterone 13
Tulathromycin 13
Doramectin 12
Moxidectin 9
Eprinomectin 9
Ivermectin 8
Enrofloxacin 6

Outcome Breakdown

Outcome Unknown
59 (40.4%)
Died
45 (30.8%)
Recovered/Normal
24 (16.4%)
Ongoing
13 (8.9%)
Euthanized
3 (2.1%)
Recovered with Sequela
2 (1.4%)

Gender Distribution

Female 58 (39.2%)
Mixed 39 (26.4%)
Male 35 (23.6%)
Unknown 16 (10.8%)

Reports by Year

Year Reports Trend
2010 15
2011 11
2012 7
2013 10
2014 9
2015 11
2016 8
2017 13
2018 12
2019 6
2020 6
2021 8
2022 10
2023 9
2024 5
2025 7
2026 1

Hereford cattle: high death-coded share in the FDA CVM extract

Signature read: Hereford cattle's 31.8% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Hereford cattle sits at #210 of 510 by report volume among all breeds and #8 of 30 among cattle breeds, with 148 reports and 47 (31.8%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #24 of 275. Mean age at report: 1.2 years, average weight 271.8 kg (599.3 lbs).

Top reported signs: Death (40), Lack of efficacy - NOS (24), Lack of efficacy (ectoparasite) - lice (17). Most-referenced drug: Dinoprost Tromethamine (13 reports), followed by Progesterone (13) and Tulathromycin (13).

Outcome coding on 146 status-recorded reports is dominated by Outcome Unknown (40.4%). Annual submissions ranged 1-2,026 across 17 years on file.

Cattle Breeds With a Similar Report Volume

Showing 6 of 29 cattle breeds in our dataset, ranked by closest report volume.

Charolais
129 reports · 38.0% death-coded
Red Angus
107 reports · 48.6% death-coded
Cattle (unspecified)
103 reports · 39.8% death-coded
Simmental
96 reports · 39.6% death-coded
Brangus
65 reports · 43.1% death-coded
Brahman
28 reports · 28.6% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Hereford cattle, both outside the Cattle family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (31.8% death-coded here).

Rabbit (unknown) 31.0% · Rabbit Rabbit (other) 36.5% · Rabbit Goat (unknown) 36.9% · Goat Crossbred Porcine/Pig 44.2% · Pig

Similar average weight

Nearest other-species breeds by reported average weight (271.8 kg here).

Pony (unspecified) 271.4 kg · Horse Hackney 271.1 kg · Horse Clydesdale 269.0 kg · Horse Pony of the Americas 278.3 kg · Horse

What to do with this cattle

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Hereford cattle? ▼
There are 148 adverse event reports involving Hereford cattle in the FDA database, of which 47 were death-coded (31.8% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Hereford cattle ranks #210 of 510 by report volume among all breeds PlainBreed indexes (#8 of 30 among cattle breeds).
Where does Hereford cattle sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Hereford cattle is #210 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cattle, it is #8 of 30. Among breeds with at least 50 reports, its death-coded share ranks #24 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Hereford cattle? ▼
The most commonly reported adverse reactions for Hereford cattle are Death (40 reports), Lack of efficacy - NOS (24 reports), Lack of efficacy (ectoparasite) - lice (17 reports), Injection site swelling (14 reports), INEFFECTIVE, ESTRUS SYNCHRONIZ (10 reports).
What drugs are most frequently associated with Hereford cattle adverse events? ▼
The drugs most frequently referenced in Hereford cattle adverse event reports are Dinoprost Tromethamine (13 reports), Progesterone (13 reports), Tulathromycin (13 reports), Doramectin (12 reports), Moxidectin (9 reports).
What is the average age of Hereford cattle in adverse event reports? ▼
The average age of Hereford cattle at the time of adverse event reports is 1.2 years, with an average weight of 271.8 kg (599.3 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hereford cattle (Cattle), extract as of July 2026 extract. 148 reports · 47 death-coded (31.8% of reports, not a mortality rate) · #210 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →