Total Reports
145
FDA CVM filings
Cattle /
2026 FDA CVM data 145 reports on file official source
Hereford cattle — FDA Adverse Event Profile
Adverse-event records and label data for Hereford cattle (Cattle), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Hereford cattle (Cattle) has 145 FDA adverse event reports on record, with 45 deaths reported (3100.0% death rate) — ranking #208 by report volume. The most frequently reported reaction is Death (39 cases). The top associated drug is Progesterone. Average age at report: 1.3 years.
Deaths Reported
45
of 145 reports
Death Rate
3100.0%
death-coded share
Avg Age at Report
1.3 yr
277.3 kg avg weight
Death-Coded Outcome Share
Hereford cattle death-coded reports 100.0%
Database median
3100.0% of 145 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 277.3 kg (611.4 lbs)
Top Reported Reactions
Death 39
Lack of efficacy - NOS 23
Lack of efficacy (ectoparasite) - lice 17
Injection site swelling 14
INEFFECTIVE, ESTRUS SYNCHRONIZ 10
Dyspnoea 6
Lack of efficacy (bacteria) - NOS 5
Hypersalivation 5
Anaphylaxis 5
Systemic disorder NOS 5
Pruritus 4
Recumbency 4
Rubbing 4
Hair loss NOS 4
Scratching 4
Most Referenced Drugs
Progesterone 13
Dinoprost Tromethamine 13
Doramectin 12
Tulathromycin 12
Moxidectin 9
Eprinomectin 9
Ivermectin 8
Enrofloxacin 5
Monensin Sodium 5
Eprinomectin 5% Injection 4
Oxytetracycline Dihydrate 4
Florfenicol/Flunixin Inj-Triac 4
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 3
Ceftiofur Crystalline Free Acid 3
Eprinomectin 5 Mg/Ml Pour-On Solution 3
Outcome Breakdown
Outcome Unknown
58 (40.6%)
Died
43 (30.1%)
Recovered/Normal
24 (16.8%)
Ongoing
13 (9.1%)
Euthanized
3 (2.1%)
Recovered with Sequela
2 (1.4%)
Gender Distribution
Female 57 (39.3%)
Mixed 37 (25.5%)
Male 35 (24.1%)
Unknown 16 (11.0%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 15 | |
| 2011 | 11 | |
| 2012 | 7 | |
| 2013 | 10 | |
| 2014 | 9 | |
| 2015 | 11 | |
| 2016 | 8 | |
| 2017 | 13 | |
| 2018 | 12 | |
| 2019 | 6 | |
| 2020 | 6 | |
| 2021 | 8 | |
| 2022 | 10 | |
| 2023 | 9 | |
| 2024 | 5 | |
| 2025 | 5 | |
Hereford cattle Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Hereford cattle accounts for 145 submitted reports and currently ranks #208 by report volume within the cattle population. Of those reports, 45 involved a death outcome — a 3100.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 1.3 years, with an average recorded body weight of 277.3 kg (611.4 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Hereford cattle are Death (39 reports), Lack of efficacy - NOS (23 reports), Lack of efficacy (ectoparasite) - lice (17 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Progesterone appears in 13 reports and is the single most-referenced drug, followed by Dinoprost Tromethamine (13) and Doramectin (12). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same cattle species.
Outcome coding on the 143 reports with a recorded status is dominated by Outcome Unknown (40.6% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual cattle.
Understanding Hereford cattle Adverse Event Data
Hereford cattle has 145 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.
The 3100.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Progesterone, appearing in 13 reports. This may indicate widespread use of the medication rather than a specific safety concern for Hereford cattle.
Other Cattle Breeds
Holstein-Friesian also known as Holstein
3,106 reports · 3890.0% death rate
Cattle (other)
2,996 reports · 4880.0% death rate
Mixed (Cattle)
2,581 reports · 4740.0% death rate
Cattle (unknown)
2,424 reports · 3850.0% death rate
Aberdeen Angus
1,610 reports · 3480.0% death rate
Crossbred Bovine/Cattle
1,357 reports · 4970.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Hereford cattle? ▼
There are 145 adverse event reports involving Hereford cattle in the FDA database, with 45 reports involving death (3100.0% death rate). Hereford cattle ranks #208 by report volume.
What are the most common adverse reactions reported for Hereford cattle? ▼
The most commonly reported adverse reactions for Hereford cattle are Death (39 reports), Lack of efficacy - NOS (23 reports), Lack of efficacy (ectoparasite) - lice (17 reports), Injection site swelling (14 reports), INEFFECTIVE, ESTRUS SYNCHRONIZ (10 reports).
What drugs are most frequently associated with Hereford cattle adverse events? ▼
The drugs most frequently referenced in Hereford cattle adverse event reports are Progesterone (13 reports), Dinoprost Tromethamine (13 reports), Doramectin (12 reports), Tulathromycin (12 reports), Moxidectin (9 reports).
What is the average age of Hereford cattle in adverse event reports? ▼
The average age of Hereford cattle at the time of adverse event reports is 1.3 years, with an average weight of 277.3 kg (611.4 lbs).
Does a high number of adverse event reports mean Hereford cattle is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Hereford cattle safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Hereford cattle ranks #208 by total report volume. Death rate (3100.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial