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Breed profile · FDA CVM July 2026 extract

Ayrshire adverse-event record

Adverse-event filings for Ayrshire (Cattle) in the FDA Center for Veterinary Medicine openFDA extract. Browse cattle breeds, reactions, and outcomes below.

#460 of 510
by report volume (all breeds)
7
FDA CVM reports on file
42.9%
death-coded share of reports
3
Death - top reaction

How the 7 reports break down

By recorded gender -- every report on file for Ayrshire, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 3 2.25 1.5 0.75 0 2010 2012 2014 2017 Reports filed Death-coded reports
Annual report volume for Ayrshire drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ayrshire ranks #460 of 510 by total reports (7). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#460
This breed, reports of 510

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ayrshire has 7 reports now versus 7 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ayrshire changes

Total Reports

7

Low report volume

Deaths Reported

3

of 7 reports

Death-coded share of reports

42.9%

42.9% death-coded

Avg Age at Report

3.2 yr

400.0 kg avg weight

Death-Coded Outcome Share

Ayrshire death-coded reports 42.9%
Cross-breed median

42.9% of 7 ayrshire reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 400.0 kg (882.0 lbs)

Top Reported Reactions

Death 3
Injection site swelling 2
Anorexia 1
Depression 1
Dependent oedema 1

Most Referenced Drugs

Oxytetracycline 1
Gamithromycin 1
Ceftiofur Crystalline Free Acid 1
Cephapirin Sodium 1
Sometribove 1

Outcome Breakdown

Died
3 (42.9%)
Outcome Unknown
2 (28.6%)
Recovered/Normal
2 (28.6%)

Gender Distribution

Female 6 (85.7%)
Male 1 (14.3%)

Reports by Year

Year Reports Trend
2010 1
2012 2
2014 3
2017 1

Ayrshire: high death-coded share in the FDA CVM extract

Signature read: 7 reports place Ayrshire in the lower third of breed filing volume (#460 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Ayrshire sits at #460 of 510 by report volume among all breeds and #25 of 30 among cattle breeds, with 7 reports and 3 (42.9%) death-coded. Mean age at report: 3.2 years, average weight 400.0 kg (882.0 lbs).

Top reported signs: Death (3), Injection site swelling (2), Anorexia (1). Most-referenced drug: Oxytetracycline (1 reports), followed by Gamithromycin (1) and Ceftiofur Crystalline Free Acid (1).

Outcome coding on 7 status-recorded reports is dominated by Died (42.9%). Annual submissions ranged 1-2,017 across 4 years on file.

Cattle Breeds With a Similar Report Volume

Showing 6 of 29 cattle breeds in our dataset, ranked by closest report volume.

Nationwide breeds with similar profiles

Sparse-volume peer sets for Ayrshire drawn from openFDA outside the Cattle family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar average weight

Nearest other-species breeds by reported average weight (400.0 kg here).

What to do with this cattle

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Ayrshire?
There are 7 adverse event reports involving Ayrshire in the FDA database, of which 3 were death-coded (42.9% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Ayrshire ranks #460 of 510 by report volume among all breeds PlainBreed indexes (#25 of 30 among cattle breeds).
Where does Ayrshire sit among other breeds in PlainBreed's corpus?
According to FDA CVM report volume, Ayrshire is #460 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cattle, it is #25 of 30. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Ayrshire?
The most commonly reported adverse reactions for Ayrshire are Death (3 reports), Injection site swelling (2 reports), Anorexia (1 reports), Depression (1 reports), Dependent oedema (1 reports).
What drugs are most frequently associated with Ayrshire adverse events?
The drugs most frequently referenced in Ayrshire adverse event reports are Oxytetracycline (1 reports), Gamithromycin (1 reports), Ceftiofur Crystalline Free Acid (1 reports), Cephapirin Sodium (1 reports), Sometribove (1 reports).
What is the average age of Ayrshire in adverse event reports?
The average age of Ayrshire at the time of adverse event reports is 3.2 years, with an average weight of 400.0 kg (882.0 lbs).

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ayrshire (Cattle), extract as of July 2026 extract. 7 reports · 3 death-coded (42.9% of reports, not a mortality rate) · #460 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →