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Breed profile · FDA CVM July 2026 extract

Charolais adverse-event record

Adverse-event filings for Charolais (Cattle) in the FDA Center for Veterinary Medicine openFDA extract. Browse cattle breeds, reactions, and outcomes below.

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#218 of 510
by report volume (all breeds)
129
FDA CVM reports on file
38.0%
death-coded share of reports
#19 of 275
by death-coded share (≥50 reports)

How the 129 reports break down

By recorded gender -- every report on file for Charolais, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 9 6.75 4.5 2.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Charolais drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Charolais ranks #218 of 510 by total reports (129) and #19 of 275 by death-coded share (38.0%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#218
This breed, reports of 510
#19
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Charolais has 129 reports now versus 128 in that prior snapshot: 1 more (0.8%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Charolais changes

Total Reports

129

Above-median volume

Deaths Reported

49

of 129 reports

Death-coded share of reports

38.0%

Highest death-coded share

Avg Age at Report

1.7 yr

268.8 kg avg weight

Death-Coded Outcome Share

Charolais death-coded reports 38.0%
Cross-breed median

38.0% of 129 charolais reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Charolais's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

38% 93rd percentile Higher share than 93% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). Below this entry. 20%–25%: 2 indexed breeds (1%). Below this entry. 25%–30%: 3 indexed breeds (1%). Below this entry. 30%–35%: 4 indexed breeds (1%). Below this entry. 35%–40%: 5 indexed breeds (2%). This entry sits in this band. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Charolais 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 268.8 kg (592.7 lbs)

Top Reported Reactions

Death 39
Lack of efficacy (ectoparasite) - lice 17
Lack of efficacy - NOS 12
Lack of efficacy (bacteria) - NOS 7
INEFFECTIVE, LICE BITING 6
Recumbency 5
Fever 5
Injection site swelling 5

Most Referenced Drugs

Doramectin 17
Ivermectin 14
Moxidectin 12
Eprinomectin 10
Tulathromycin 8
Ivermectin 0.5% Pour-On Topical Solution 8
Monensin Sodium 5
Tildipirosin Injectable 5

Outcome Breakdown

Outcome Unknown
46 (36.2%)
Died
44 (34.6%)
Recovered/Normal
16 (12.6%)
Ongoing
9 (7.1%)
Euthanized
6 (4.7%)
Recovered with Sequela
6 (4.7%)

Gender Distribution

Female 44 (34.1%)
Male 38 (29.5%)
Mixed 36 (27.9%)
Unknown 11 (8.5%)

Reports by Year

Year Reports Trend
2010 11
2011 8
2012 5
2013 12
2014 14
2015 9
2016 14
2017 7
2018 10
2019 3
2020 9
2021 6
2022 7
2023 8
2024 2
2025 3
2026 1

Charolais: high death-coded share in the FDA CVM extract

Signature read: Charolais's 38.0% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Charolais sits at #218 of 510 by report volume among all breeds and #9 of 30 among cattle breeds, with 129 reports and 49 (38.0%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #19 of 275. Mean age at report: 1.7 years, average weight 268.8 kg (592.7 lbs).

Top reported signs: Death (39), Lack of efficacy (ectoparasite) - lice (17), Lack of efficacy - NOS (12). Most-referenced drug: Doramectin (17 reports), followed by Ivermectin (14) and Moxidectin (12).

Outcome coding on 127 status-recorded reports is dominated by Outcome Unknown (36.2%). Annual submissions ranged 1-2,026 across 17 years on file.

Cattle Breeds With a Similar Report Volume

Showing 6 of 29 cattle breeds in our dataset, ranked by closest report volume.

Hereford cattle
148 reports · 31.8% death-coded
Red Angus
107 reports · 48.6% death-coded
Cattle (unspecified)
103 reports · 39.8% death-coded
Simmental
96 reports · 39.6% death-coded
Brangus
65 reports · 43.1% death-coded
Brahman
28 reports · 28.6% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Charolais, both outside the Cattle family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (38.0% death-coded here).

Goat (unknown) 36.9% · Goat Rabbit (other) 36.5% · Rabbit Crossbred Porcine/Pig 44.2% · Pig Rabbit (unknown) 31.0% · Rabbit

Similar average weight

Nearest other-species breeds by reported average weight (268.8 kg here).

Clydesdale 269.0 kg · Horse Hackney 271.1 kg · Horse Pony (unspecified) 271.4 kg · Horse Pony of the Americas 278.3 kg · Horse

What to do with this cattle

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Charolais? ▼
There are 129 adverse event reports involving Charolais in the FDA database, of which 49 were death-coded (38.0% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Charolais ranks #218 of 510 by report volume among all breeds PlainBreed indexes (#9 of 30 among cattle breeds).
Where does Charolais sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Charolais is #218 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cattle, it is #9 of 30. Among breeds with at least 50 reports, its death-coded share ranks #19 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Charolais? ▼
The most commonly reported adverse reactions for Charolais are Death (39 reports), Lack of efficacy (ectoparasite) - lice (17 reports), Lack of efficacy - NOS (12 reports), Lack of efficacy (bacteria) - NOS (7 reports), INEFFECTIVE, LICE BITING (6 reports).
What drugs are most frequently associated with Charolais adverse events? ▼
The drugs most frequently referenced in Charolais adverse event reports are Doramectin (17 reports), Ivermectin (14 reports), Moxidectin (12 reports), Eprinomectin (10 reports), Tulathromycin (8 reports).
What is the average age of Charolais in adverse event reports? ▼
The average age of Charolais at the time of adverse event reports is 1.7 years, with an average weight of 268.8 kg (592.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Charolais (Cattle), extract as of July 2026 extract. 129 reports · 49 death-coded (38.0% of reports, not a mortality rate) · #218 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →